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      • Record: found
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      PEGylated liposomes associate with Wnt3A protein and expand putative stem cells in human bone marrow populations.

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          Abstract

          To fabricate PEGylated liposomes which preserve the activity of hydrophobic Wnt3A protein, and to demonstrate their efficacy in promoting expansion of osteoprogenitors from human bone marrow.

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Nanomedicine (Lond)
          Title: Nanomedicine (London, England)
          Publisher: Future Medicine Ltd
          ISSN (Electronic): 1748-6963
          ISSN (Print): 1743-5889
          Publication date (Electronic): April 2017
          Volume: 12
          Issue: 8
          Affiliations
          [1 ] Human Development & Health Academic Unit, Faculty of Medicine, Centre for Human Development, Stem Cells & Regeneration, Bone & Joint Research Group & Institute for Life Sciences, Institute for Developmental Sciences, University of Southampton, Tremona Road, Southampton, SO16 6YD, UK.
          [2 ] Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK.
          [3 ] Microbiology Group, Chemical, Biological & Radiological Division, Dstl, Porton Down, Salisbury, SP4 0JQ, UK.
          [4 ] Clinical & Experimental Sciences, Faculty of Medicine, Institute for Life Sciences, University of Southampton, Building 85, Life Sciences Building, Highfield Campus, Southampton, SO17 1BJ, UK.
          Article
          DOI: 10.2217/nnm-2016-0386
          PubMed ID: 28351228
          SO-VID: 0ebe99b0-6b7e-4226-b3d6-2f3a14843969
          History

          Keywords: liposomes,marrow stromal cells,regenerative medicine,osteoprogenitors,fracture repair,mesenchymal stem cells,skeletal stem cells,PEGylated liposomes,Wnt
          Data availability:
          Keywords: liposomes, marrow stromal cells, regenerative medicine, osteoprogenitors, fracture repair, mesenchymal stem cells, skeletal stem cells, PEGylated liposomes, Wnt

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