Hypercalcitoninemia in a Sporadic Asymptomatic Neuroendocrine Tumor of the Pancreatic Tail

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Background/Aim: Asymptomatic neuroendocrine tumors of the gastroenteropancreatic tract represent a significant challenge in terms of postoperative monitoring. Methods: A case report of a calcitonin-secreting asymptomatic neuroendocrine tumor of the pancreatic tail is presented. Results: Hypercalcitoninemia was noted in the 76-year-old Caucasian man who had a recurrent neuroendocrine tumor of the pancreatic tail. Upon pentagastrin stimulation, basal calcitonin increased only moderately from 82.3 (<10) to 100.9 and 125 pg/ml after 2 and 5 min, respectively. Surgical removal of the neuroendocrine tumor resulted in postoperative normalization of both basal and stimulated serum calcitonin levels. On immunohistochemistry, the neuroendocrine tumor was positive for calcitonin. Conclusion: Routine measurements of serum calcitonin might be a highly sensitive adjunct capable of identifying a subset of neuroendocrine tumors in which calcitonin monitoring may aid in the early detection of postoperative recurrence.

Related collections

Author and article information

Journal

Journal ID (publisher-id): DSU

Journal ID (nlm-ta): Dig Surg

Journal ID (doi): 10.1159/issn.0253-4886

Title: Digestive Surgery

Publisher: S. Karger AG

ISSN (Print): 0253-4886

ISSN (Electronic): 1421-9883

Publication date Subscription-year: 2000

Publication date (Print): 2000

Publication date (Electronic): 11 December 2000

Volume: 17

Issue: 5

Pages: 522-524

Affiliations

Departments of ^aGeneral Surgery, ^bInternal Medicine, Division of Endocrinology, and ^cPathology, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany

Article

Publisher ID: 51953 Other ID: Dig Surg 2000;17:522–524

DOI: 10.1159/000051953

PubMed ID: 11124561

SO-VID: 104460ec-96ac-42d1-8988-f8a7fbebc688

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Page count

Figures: 1, References: 5, Pages: 3

Comments

Comment on this article

scite_

Cited by 5

See all cited by

- Version 1

Call for Papers: Artificial Intelligence in Gastroenterology

Submit here before May 31, 2024