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      Protter: interactive protein feature visualization and integration with experimental proteomic data.

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          Abstract

          The ability to integrate and visualize experimental proteomic evidence in the context of rich protein feature annotations represents an unmet need of the proteomics community. Here we present Protter, a web-based tool that supports interactive protein data analysis and hypothesis generation by visualizing both annotated sequence features and experimental proteomic data in the context of protein topology. Protter supports numerous proteomic file formats and automatically integrates a variety of reference protein annotation sources, which can be readily extended via modular plug-ins. A built-in export function produces publication-quality customized protein illustrations, also for large datasets. Visualizations of surfaceome datasets show the specific utility of Protter for the integrated visual analysis of membrane proteins and peptide selection for targeted proteomics.

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          Author and article information

          Journal
          Bioinformatics
          Bioinformatics (Oxford, England)
          Oxford University Press (OUP)
          1367-4811
          1367-4803
          Mar 15 2014
          : 30
          : 6
          Affiliations
          [1 ] Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, 8093 Zürich and Institute of Molecular Life Sciences, University of Zürich, 8057 Zürich, Switzerland.
          Article
          btt607
          10.1093/bioinformatics/btt607
          24162465

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