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      Robotic Management of Urolithiasis in the Pediatric Population

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          Abstract

          A variety of surgical techniques exist for the management of urolithiasis. Minimally invasive techniques have replaced open surgery in the last few decades. For complex stone management, robotic-assisted laparoscopic surgery (RALS) has emerged as a safe and feasible alternative in adults. The literature for RALS for urolithiasis (RALS-UL) in the pediatric population is scarce. Herein, we present a review of the literature in both adult and pediatric patients as well as our experience using RALS-UL at our institutions. Special attention is given to the synchronous management of urolithiasis when surgery is performed for other conditions such as ureteropelvic junction obstruction (UPJO), and a supplemental video is provided.

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          Most cited references36

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          Robotic dismembered pyeloplasty: a 6-year, multi-institutional experience.

          The introduction of the da Vinci Surgical System to perform complex reconstructive procedures, such as repair of ureteropelvic junction obstruction, has helped to overcome some of the technical challenges associated with laparoscopy. We review our large multi-institutional experience with long-term followup of robotic dismembered pyeloplasty. A total of 140 patients from 3 university medical centers underwent robotic dismembered pyeloplasty. An institutional review board approved retrospective chart review was performed to collect demographic, preoperative, operative and postoperative data. Patients were analyzed as an entire cohort and then divided into various subgroups. Of the cases 117 (84.6%) were primary repairs and 23 (16.4%) were secondary repairs. There were 13 (9.3%) patients who underwent concomitant stone extraction and 5 (3.6%) procedures were performed on patients with solitary kidneys. A crossing vessel was found in 77 (55%) patients. Mean operative time was 217 minutes (range 80 to 510), estimated blood loss was 59.4 ml (range 10 to 600), mean length of hospital stay 2.1 days (range 0.75 to 7) and mean followup was 29 months (range 3 to 63). Radiographic resolution of obstruction on first postoperative diuretic renal scan or excretory urogram was noted in 134 patients (95.7%). There was a 7.1% major complication rate and a 2.9% minor complication rate. No statistically significant differences were found in any parameters among patients from the various cohorts. To our knowledge this review represents the largest multi-institutional experience of robotic dismembered pyeloplasty with long-term followup. Robotic pyeloplasty appears to be safe, durable and efficacious for primary and secondary ureteropelvic junction obstruction with or without concomitant stone extraction, and for patients with a solitary kidney.
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            Concomitant management of renal calculi and pelvi-ureteric junction obstruction with robotic laparoscopic surgery.

            To present technical recommendations for robotic-assisted laparoscopic pyeloplasty (RALP) and stone extraction, as patients with kidney stones proximal to a pelvi-ureteric junction obstruction (PUJO) present a technical challenge, and have traditionally been managed with open surgery or percutaneous antegrade endopyelotomy. From November 2002 to April 2005, 55 patients had RALP for PUJO; eight of these had concomitant renal calculi. Stone burden and location were assessed with a preoperative radiological examination. Before completing the PUJO repair, one robot working arm (cephalad one) was temporarily undocked to allow passage of a flexible nephroscope into the renal pelvis and collecting systems under direct vision. Stones were extracted with graspers or basket catheters and removed via the port. The surgical-assistant port in the subxiphoid area was used to introduce laparoscopic suction and other instruments. The Anderson-Hynes dismembered pyeloplasty was the preferred reconstructive technique in all patients. Operations were completed robotically with no conversions to open surgery. All patients were rendered stone-free, confirmed by imaging, and there were no intraoperative or delayed complications during a mean (range) follow-up of 12.3 (4-22) months. The mean operative time was 275.8 min, 61.7 min longer than in patients who did not have concomitant stone removal. Concurrent stone extraction and PUJO repair can be successful with RALP. Operative times are longer than in patients with isolated PUJO repair, but this is to be expected as there is an additional procedure.
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              Early results of robot assisted laparoscopic lithotomy in adolescents.

              The treatment of large stone burdens in children is difficult and often requires multiple procedures using a combination of therapies. Recently, laparoscopy has been shown to be effective in the management of larger stone burdens. We report our experience with robot assisted laparoscopic lithotomy in adolescents, and describe our technique. We retrospectively reviewed our experience with robot assisted laparoscopic pyelolithotomy in 5 patients operated on between 2002 and 2005. Mean patient age at surgery was 16.6 years, and mean followup was 15.4 months. Cystine was the etiology in 4 patients with staghorn stones. The remaining patient had calcium oxalate stones and concurrent ureteropelvic junction obstruction. After pyelotomy stones were removed by a robotic grasper or by a flexible cystoscope introduced through a robotic port. One of the patients had an indwelling ureteral stent placed preoperatively, while 4 had stents placed robotically intraoperatively. Mean operative time was 315.4 minutes (range 165.0 to 462.0), and mean estimated blood loss was 19.0 ml (0.0 to 50.0). Mean hospital stay was 3.8 days (range 2.3 to 5.7), and mean narcotic usage was 2.1 mg/kg morphine (1.5 to 3.5). One patient with a cystine staghorn calculus required conversion to an open procedure because of inability to remove the stone. Of the 4 cases completed robotically 3 were rendered stone-free and 1 had a residual 6 mm lower pole stone. The early results of robot assisted laparoscopic lithotomy reveal that the procedure is safe and efficacious. Further prospective studies comparing other minimally invasive procedures used for similar stone burdens are needed to determine the benefits of this procedure and its role in stone management.
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                Author and article information

                Contributors
                Journal
                Front Pediatr
                Front Pediatr
                Front. Pediatr.
                Frontiers in Pediatrics
                Frontiers Media S.A.
                2296-2360
                22 August 2019
                2019
                : 7
                : 351
                Affiliations
                [1] 1Division of Pediatric Urology, Nicklaus Children's Hospital , Miami, FL, United States
                [2] 2Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University , Fort Lauderdale, FL, United States
                [3] 3Division of Pediatric Urology, Jackson Memorial Hospital , Miami, FL, United States
                [4] 4Division of Pediatric Urology, Florida Hospital for Children , Orlando, FL, United States
                [5] 5Division of Pediatric Urology, Joe DiMaggio Children's Hospital , Hollywood, FL, United States
                Author notes

                Edited by: Sajid Sultan, Sindh Institute of Urology and Transplantation, Pakistan

                Reviewed by: Mohan S. Gundeti, University of Chicago, United States; Matthieu Peycelon, Indiana University, United States; Roberto Luis Vagni, Italian Hospital of Buenos Aires, Argentina

                *Correspondence: Natalia Ballesteros natabal4@ 123456gmail.com

                This article was submitted to Pediatric Urology, a section of the journal Frontiers in Pediatrics

                Article
                10.3389/fped.2019.00351
                6714108
                31508400
                10a10d1a-8115-47a9-830c-0d9b1a37baf0
                Copyright © 2019 Ballesteros, Snow, Moscardi, Ransford, Gomez and Castellan.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 04 January 2019
                : 06 August 2019
                Page count
                Figures: 3, Tables: 0, Equations: 0, References: 43, Pages: 8, Words: 5991
                Categories
                Pediatrics
                Review

                robotic,pyelolithotomy,nephrolithotomy,urolithiasis,renal stones,ureteropelvic junction obstruction,pediatric

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