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Kappa-opioid receptor agonist protects the microcirculation of skeletal muscle from ischemia reperfusion injury.

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Annals of plastic surgery

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      Abstract

      Previous research has demonstrated that pretreatment with kappa opioid receptor (KOR) agonist protects against ischemia reperfusion (I/R) injury in cardiomyocytes and neuron cells through activation of protein kinase C. The purpose of this study is to investigate the KOR agonist's effect on I/R-injured cremaster muscle and its underlying mechanism.

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      Author and article information

      Affiliations
      [1] Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.
      Journal
      Ann Plast Surg
      Annals of plastic surgery
      1536-3708
      0148-7043
      Sep 2008
      : 61
      : 3
      18724138
      10.1097/SAP.0b013e31815b9e64
      00000637-200809000-00022

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