Receptor activity-modifying protein-1 augments cerebrovascular responses to calcitonin gene-related peptide and inhibits angiotensin II-induced vascular dysfunction.

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Abstract

Receptors for calcitonin gene-related peptide (CGRP) are composed of the calcitonin-like receptor in association with receptor activity-modifying protein-1 (RAMP1). CGRP is an extremely potent vasodilator and may protect against vascular disease through other mechanisms.

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Author and article information

Journal

Journal ID (iso-abbrev): Stroke

Title: Stroke

Publisher: Ovid Technologies (Wolters Kluwer Health)

ISSN (Electronic): 1524-4628

ISSN (Print): 0039-2499

Publication date (Electronic): Oct 2010

Volume: 41

Issue: 10

Affiliations

[1 ] Department of Internal Medicine, Cardiovascular Center, The University of Iowa Carver College of Medicine, Iowa City, Iowa 52242-1081, USA.

Article

Publisher Item ID: STROKEAHA.110.589648 Mid ID: NIHMS237404

DOI: 10.1161/STROKEAHA.110.589648

PMC ID: 3063064

PubMed ID: 20814003

SO-VID: 139a5925-6d89-4562-b981-3a1919d1370e

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