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      Quality of life impairment after a diagnosis of Cushing’s syndrome

      review-article
      1 , , 2
      Pituitary
      Springer US
      Quality of life, Cushing syndrome, Memory impairment, Anxiety, Depression, Emotional distress

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          Abstract

          This brief review is devoted mainly to publications in the last 5 years dealing with health-related quality of life (QoL) after a diagnosis of endogenous hypercortisolism, due to pituitary-dependent Cushing’s disease (CD) or any other cause of Cushing syndrome (CS). Despite improvement after treatment, persistent physical morbidity, neurocognitive problems like worse executive capacity and memory as well as stress intolerance, depressive symptoms and more anxiety, lead to long-term impairment of QoL.

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          Most cited references15

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          Psychiatric and neurocognitive consequences of endogenous hypercortisolism

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            Hippocampal Volume, Cognitive Functions, Depression, Anxiety, and Quality of Life in Patients With Cushing Syndrome.

            Cushing syndrome (CS) is associated with hippocampal atrophy and psychopathology.
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              Worse Health-Related Quality of Life at long-term follow-up in patients with Cushing's disease than patients with cortisol producing adenoma. Data from the ERCUSYN

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                Author and article information

                Contributors
                webbsusan4@gmail.com
                Journal
                Pituitary
                Pituitary
                Pituitary
                Springer US (New York )
                1386-341X
                1573-7403
                29 June 2022
                29 June 2022
                2022
                : 25
                : 5
                : 768-771
                Affiliations
                [1 ]GRID grid.7080.f, ISNI 0000 0001 2296 0625, Endocrinology Dept, Hospital Sant Pau, IIB-Sant Pau, , Research Center for Pituitary Diseases; Dept Medicine, Universitat Autònoma de Barcelona (UAB), ; CIBERER, Unit 747, ISCIII, 08041 Barcelona, Spain
                [2 ]GRID grid.410675.1, ISNI 0000 0001 2325 3084, Endocrinology Dept, Germans Trias i Pujol Hospital & Research Institute, , Universitat Internacional de Catalunya (UIC), ; CIBERER, Unit 747, ISCIII, 08916 Badalona, Spain
                Author information
                http://orcid.org/0000-0001-7052-6436
                http://orcid.org/0000-0002-3864-0105
                Article
                1245
                10.1007/s11102-022-01245-9
                9587961
                35767164
                14a7851d-35d3-4923-bd6a-b2be86c3d6e0
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

                History
                : 21 April 2022
                : 16 June 2022
                Categories
                Review
                Custom metadata
                © Springer Science+Business Media, LLC, part of Springer Nature 2022

                Medicine
                quality of life,cushing syndrome,memory impairment,anxiety,depression,emotional distress
                Medicine
                quality of life, cushing syndrome, memory impairment, anxiety, depression, emotional distress

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