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      Toxic epidermal necrolysis associated with pembrolizumab.

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          Abstract

          Stevens-Johnson syndrome and toxic epidermal necrolysis are severe cutaneous drug eruptions characterized by epidermal detachment. Pembrolizumab is a monoclonal antibody that binds to the programmed death-1 receptor, and it has been associated with numerous cutaneous adverse side-effects, including Stevens-Johnson syndrome.

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          Author and article information

          Journal
          J Oncol Pharm Pract
          Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
          SAGE Publications
          1477-092X
          1078-1552
          Jul 2020
          : 26
          : 5
          Affiliations
          [1 ] Department of Dermatology, Centre Hospitalier de l'Université de Montréal, Québec, Canada.
          [2 ] Department of Pharmacy, Centre Hospitalier de l'Université de Montréal, Québec, Canada.
          [3 ] Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Québec, Canada.
          [4 ] Department of Medicine, Service of Hematology, Oncology and Blood Bank, Centre Hospitalier de l'Université de Montréal, Québec, Canada.
          [5 ] Department of Medicine, Centre intégré de santé et des services sociaux de l'Outaouais, Québec, Canada.
          [6 ] Department of Pathology, Centre Hospitalier de l'Université de Montréal, Québec, Canada.
          Article
          10.1177/1078155219890659
          31810421
          14c0268b-3864-4b7f-a20c-db54b25d5f27
          History

          pembrolizumab,immunotherapy,immune-related adverse events,Adverse reaction,toxic epidermal necrolysis

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