Objective To understand the serum vitamin A level of children aged 0- 16 years in Nantong City, and to provide reference for scientific supplement of vitamin A for children and prevention of related diseases.
Methods A cross-sectional survey method was used to detect the serum vitamin A level of 3 271 children aged 0-16 years old by using high performance liquid chromatography (HPLC) in Nantong Maternal and Child Health hospital from January 2017 to December 2018, and the general information of children was collected.
Results The results showed that the average serum vitamin A concentration of 0-16 years old children was (0.31±0.08) mg/L, boys was (0.31±0.08) mg/L, which was lower than that of girls (0.32±0.09) mg/L. The proportion of insufficient and deficient vitamin A in boys was higher than that in girls ( P<0.01) ; The levels of serum vitamin A were different by age groups, from high to low were >12〜16, >6 〜12, >3 〜6, >1〜3, ≤1 years old, the difference was statistically significant ( F = 3.48, P<0.05). The results showed that the proportion of normal, insufficient and deficient vitamin A in rural children were 51.2%, 43.5% and 5.3%, respectively. The proportion of vitamin A deficiency and deficiency in rural children was higher than that in urban areas (χ 2 = 18.86, P<0.01).
Conclusion The proportion of vitamin A insufficieng and deficiency among children in Nantong is higher, boys show worse vitamin A status compared of girls. More attention should be paided diseases.
【摘要】 目的 了解南通市 0~16 岁儿童血清维生素A水平, 为儿童科学补充维生素A及有关部门预防相关疾病提供参 考依据。 方法 采用横断面调査的方法, 于 2017 年 1 月至 2018 年 12 月, 采用髙效液相色谱法 (High Performance Liquid Chromatography, HPLC) 检测至南通市妇幼保健院体检的 3 271 名 0~16 岁儿童血清维生素A水平, 并记录儿童的基本信 息。 结果 0~16 岁儿童血清维生素A平均质量体积浓度为 (0.31±0.08)mg/L, 其中男童为 (0.31±0.08)mg/L, 低于女童的 (0.32±0.09)mg/L, 男童维生素A不足和缺乏的比例髙于女童, 差异均有统计学意义 ( P 值均<0.01 );不同年龄段儿童血清 维生素A水平不同, 从髙到低依次为 >12~16、>6~12、>3~6、>1~3、≤1岁, 差异有统计学意义 ( F = 3.48, P<0.05);维生素 A正常、不足、缺乏的比例依次为 51.2%, 43.5% 和 5.3%, 农村儿童维生素A不足和缺乏的比例髙于城镇, 差异有统计学意 义 (χ 2 = 18.86, P<0.01 )。 结论 南通地区儿童维生素A不足和缺乏的比例较髙, 男童维生素A营养状况较女童差, 应更 多关注这部分儿童, 并预防相关疾病。