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      Awareness and perception of pharmacy researchers about conflict of interest: A study from the MENA region

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          Abstract

          The literature has shown some bias in research about the effectiveness and efficacy of medications due to the influence of the pharmaceutical industry. Thus, researchers’ understanding of conflict of interest (COI) is substantial and may influence the quality of scientific research. Therefore, in this study, we aimed to assess pharmacy researchers’ awareness and perception about COI in the Middle East and North Africa (MENA) region and the factors affecting their disclosure of COI. In this cross-sectional study, a convenience sample of pharmacy researchers from the MENA region was surveyed for their awareness and perception about the principles of COI. The questionnaire was divided into three main sections. The first section assesses the demographic information of the study participants; the second section assesses researchers’ awareness and practices in dealing with COI; and, finally, the third section assesses participants’ perception about COI. The questionnaire was uploaded on the Google Forms electronic platform, and it was distributed to the potential study participants via their professional emails. Finally, logistic analysis was used to evaluate predictors affecting COI disclosure by the study participants. A total of 271 pharmacy researchers participated in this study. Researchers were distributed based on their academic rank as follows: 63 professors (23.3%), 59 associate professors (21.8%), 97 assistant professors (35.8%), and 52 lecturers (19.2%). The majority of researchers indicated that they were familiar with the concept of COI (88.9%), and they agreed that the existence of COI should be disclosed by all authors (84.5%). About 33.2% of the study participants did not know if their institution had a policy for COI. About half of the participants (48.70%) believed that disclosure is the only way for the management of COI. However, only 41.7% of them ( n = 113) indicated that they had disclosed COI in their published research. Finally, participants who have a collaboration with the industry showed a significantly lower tendency to disclose their COI than those who do not have any partnership with the industry (OR = 0.471, p = 0.017). The majority of the pharmacy researchers from the MENA region are familiar with the principles of COI, but a lower percentage of them disclose their COI in their published research. Efforts should be made to educate researchers about the importance of disclosing COI, which might reduce the potential of bias in their published research.

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          Most cited references56

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          World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects.

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            Industry sponsorship and research outcome.

            Clinical research affecting how doctors practice medicine is increasingly sponsored by companies that make drugs and medical devices. Previous systematic reviews have found that pharmaceutical-industry sponsored studies are more often favorable to the sponsor's product compared with studies with other sources of sponsorship. A similar association between sponsorship and outcomes have been found for device studies, but the body of evidence is not as strong as for sponsorship of drug studies. This review is an update of a previous Cochrane review and includes empirical studies on the association between sponsorship and research outcome.
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              Addressing Bias and Conflict of Interest Among Biomedical Researchers

              Lisa Bero (2017)
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                Author and article information

                Journal
                101580174
                46921
                J Appl Pharm Sci
                J Appl Pharm Sci
                Journal of applied pharmaceutical science
                2231-3354
                9 March 2023
                August 2022
                04 August 2022
                22 March 2023
                : 12
                : 8
                : 148-155
                Affiliations
                [1 ]Department of Pharmaceutical Technology, Jordan University of Science and Technology, Irbid 22110, Jordan
                [2 ]Department of Pharmacy Practice and Pharmacotherapeutics, University of Sharjah, Sharjah, UAE.
                [3 ]Department of Clinical Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan
                [4 ]Department of Medical Laboratory Sciences, Jordan University of Science and Technology, Irbid 22110, Jordan
                [5 ]Department of Clinical Pharmacy and Therapeutics, Faculty of Pharmacy, Applied Science Private University, Amman 11931, Jordan
                Author notes

                AUTHORS’ CONTRIBUTIONS

                Hadeia Mashaqhbeh, Karem H. Alzoubi, and Omar F. Khabour contributed to the study design, data collection, and manuscript writing. Rana Abu-Farha contributed to study design, data analysis, and manuscript writing.

                [* ]Corresponding Author Karem Alzoubi, University of Sharjah, Sharjah, United Arab Emirates. khalzoubi@ 123456just.edu.jo
                Article
                NIHMS1880969
                10.7324/japs.2022.120815
                10032366
                36960216
                15a4b236-58e0-49b5-a57e-f50bdef7967d

                This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License ( https://creativecommons.org/licenses/by/4.0/).

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                pharmacy researchers,attitude,conflict of interest,mena
                pharmacy researchers, attitude, conflict of interest, mena

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