Contributors
Sunao Shimizu:
ORCID: http://orcid.org/0000-0002-8183-4677
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Junsei Mimura: Role: Investigation
Takanori Hasegawa: Role: Formal analysis
Eigo Shimizu: Role: Formal analysis
Seiya Imoto: Role: Formal analysisRole: MethodologyRole: Project administration
Michiko Tsushima: Role: SupervisionRole: Writing – review & editing
Shuya Kasai: Role: InvestigationRole: Writing – review & editing
Hiromi Yamazaki: Role: Project administrationRole: Writing – review & editing
Yusuke Ushida: Role: Project administration
Hiroyuki Suganuma: Role: Supervision
Hirofumi Tomita: Role: Writing – review & editing
Masayuki Yamamoto: Role: Formal analysis
Shigeyuki Nakaji: Role: ConceptualizationRole: Funding acquisitionRole: Supervision
Ken Itoh:
ORCID: http://orcid.org/0000-0002-5518-0729
Role: ConceptualizationRole: Data curationRole: Formal analysisRole: Funding acquisitionRole:
InvestigationRole: MethodologyRole: Project administrationRole: SupervisionRole: ValidationRole:
VisualizationRole: Writing – original draftRole: Writing – review & editing
Hiroyuki Itabe: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
11
August
2020
Publication date Collection: 2020
Volume: 15
Issue: 8
Electronic Location Identifier: e0236834
Affiliations
[1
]
Department of Stress Response Science, Center for Advanced Medical Research, Hirosaki
University Graduate School of Medicine, Hirosaki, Japan
[2
]
Department of Vegetable Life Science, Hirosaki University Graduate School of Medicine,
Hirosaki, Japan
[3
]
Department of Nature & Wellness Research, Innovation Division, Kagome Co., Ltd. Nasushiobara,
Tochigi, Japan
[4
]
Health Intelligence Center, The University of Tokyo, Minato-ku, Tokyo, Japan
[5
]
Human Genome Center, The Institute of Medical Science, The University of Tokyo, Minato-ku,
Tokyo, Japan
[6
]
Department of Cardiology and Nephrology, Hirosaki University Graduate School of Medicine,
Hirosaki, Japan
[7
]
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan
[8
]
Department of Social Medicine, Hirosaki University Graduate School of Medicine, Hirosaki,
Japan
Showa University School of Pharmacy, JAPAN
Author notes
Competing Interests: The authors have declared that no competing interests exist. This does not alter our
adherence to PLOS ONE policies on sharing data and materials.
[¤]
Current address: Department of Hematology-Oncology, Institute of Biomedical Research
and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan
Author information
Article
Publisher ID:
PONE-D-20-12583
DOI: 10.1371/journal.pone.0236834
PMC ID: 7418968
PubMed ID: 32780748
SO-VID: 174f306e-b849-4222-a8a5-e8b7e649a940
Copyright © © 2020 Shimizu et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 30
April
2020
Date
accepted
: 14
July
2020
Page count
Figures: 3,
Tables: 3,
Pages: 17
Funding
Funded by: funder-id http://dx.doi.org/10.13039/501100009033, Center of Innovation Program;
Award ID: JPMJCE1302
Award Recipient
:
Shigeyuki Nakaji
Funded by: funder-id http://dx.doi.org/10.13039/501100009033, Center of Innovation Program;
Award ID: JPMJCE1302
Award Recipient
:
ORCID: http://orcid.org/0000-0002-5518-0729
Ken Itoh
This work was supported by "Center for Innovation Program" of the Japan Science and
Technology Agency Grant Number JPMJCE1302 (
https://projectdb.jst.go.jp/grant/JST-PROJECT-13423993/) and Joint Research Costs for the Department of Vegetable Life Science from Kagome
Co., Ltd. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript. The Kagome Co., Ltd. provided support
in the form of salaries for authors [SS, YU and HS] and the research costs as the
Joint Research Costs, but did not have any additional roles in the study design, data
collection and analysis, decision to publish, or preparation of the manuscript. The
specific roles of these authors are articulated in the ‘author contributions’ section.
SS: Sunao Shimizu, YU: Yusuke Ushida, HS: Hiroyuki Suganuma.
Categories
Subject:
Research Article
Subject:
Physical Sciences
Subject:
Materials Science
Subject:
Material Properties
Subject:
Mechanical Properties
Subject:
Stiffness
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Medicine and Health Sciences
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Vascular Medicine
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Blood Pressure
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Biology and Life Sciences
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Biochemistry
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Lipids
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Cholesterol
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Medicine and Health Sciences
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Medical Conditions
Subject:
Cardiovascular Diseases
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Medicine and Health Sciences
Subject:
Cardiology
Subject:
Cardiovascular Medicine
Subject:
Cardiovascular Diseases
Subject:
Medicine and Health Sciences
Subject:
Vascular Medicine
Subject:
Atherosclerosis
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Cardiovascular Diseases
Subject:
Cardiovascular Disease Risk
Subject:
Medicine and Health Sciences
Subject:
Cardiology
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Cardiovascular Medicine
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Cardiovascular Diseases
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Cardiovascular Disease Risk
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Biology and Life Sciences
Subject:
Molecular Biology
Subject:
Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
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Research and Analysis Methods
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Molecular Biology Techniques
Subject:
Artificial Gene Amplification and Extension
Subject:
Polymerase Chain Reaction
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Biomarkers
Subject:
Creatinine
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