For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
0
views
134
references
 Top references
cited by
0
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      196
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Summary

          Esophagectomy is an exemplar of complex oncological surgery and is associated with a relatively high risk of major morbidity and mortality. In the modern era, where specific complications are targeted in prevention and treatment pathways, and where the principles of enhanced recovery after surgery are espoused, optimum outcomes are targeted via a number of approaches. These include comprehensive clinical and physiological risk assessment, specialist perioperative care by a high-volume team, and multimodal inputs throughout the patient journey that aim to preserve or restore nutritional deficits, muscle mass and function.

          Related collections

          Most cited references134

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          Sarcopenia: revised European consensus on definition and diagnosis

          Alfonso Cruz-Jentoft, Gulistan Bahat, Jürgen Bauer … (2018)
          Abstract Background in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings. Objectives to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia. Recommendations sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia. Conclusions EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.
          Article 0 comments Cited 2769 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            A global clinical measure of fitness and frailty in elderly people.

            Kenneth Rockwood, Xiaowei Song, Chris MacKnight … (2005)
            There is no single generally accepted clinical definition of frailty. Previously developed tools to assess frailty that have been shown to be predictive of death or need for entry into an institutional facility have not gained acceptance among practising clinicians. We aimed to develop a tool that would be both predictive and easy to use. We developed the 7-point Clinical Frailty Scale and applied it and other established tools that measure frailty to 2305 elderly patients who participated in the second stage of the Canadian Study of Health and Aging (CSHA). We followed this cohort prospectively; after 5 years, we determined the ability of the Clinical Frailty Scale to predict death or need for institutional care, and correlated the results with those obtained from other established tools. The CSHA Clinical Frailty Scale was highly correlated (r = 0.80) with the Frailty Index. Each 1-category increment of our scale significantly increased the medium-term risks of death (21.2% within about 70 mo, 95% confidence interval [CI] 12.5%-30.6%) and entry into an institution (23.9%, 95% CI 8.8%-41.2%) in multivariable models that adjusted for age, sex and education. Analyses of receiver operating characteristic curves showed that our Clinical Frailty Scale performed better than measures of cognition, function or comorbidity in assessing risk for death (area under the curve 0.77 for 18-month and 0.70 for 70-month mortality). Frailty is a valid and clinically important construct that is recognizable by physicians. Clinical judgments about frailty can yield useful predictive information.
            Article 0 comments Cited 1646 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Multi-ethnic reference values for spirometry for the 3-95-yr age range: the global lung function 2012 equations.

              Philip H. Quanjer, Sanja Stanojevic, Tim J. Cole … (2012)
              The aim of the Task Force was to derive continuous prediction equations and their lower limits of normal for spirometric indices, which are applicable globally. Over 160,000 data points from 72 centres in 33 countries were shared with the European Respiratory Society Global Lung Function Initiative. Eliminating data that could not be used (mostly missing ethnic group, some outliers) left 97,759 records of healthy nonsmokers (55.3% females) aged 2.5-95 yrs. Lung function data were collated and prediction equations derived using the LMS method, which allows simultaneous modelling of the mean (mu), the coefficient of variation (sigma) and skewness (lambda) of a distribution family. After discarding 23,572 records, mostly because they could not be combined with other ethnic or geographic groups, reference equations were derived for healthy individuals aged 3-95 yrs for Caucasians (n=57,395), African-Americans (n=3,545), and North (n=4,992) and South East Asians (n=8,255). Forced expiratory value in 1 s (FEV(1)) and forced vital capacity (FVC) between ethnic groups differed proportionally from that in Caucasians, such that FEV(1)/FVC remained virtually independent of ethnic group. For individuals not represented by these four groups, or of mixed ethnic origins, a composite equation taken as the average of the above equations is provided to facilitate interpretation until a more appropriate solution is developed. Spirometric prediction equations for the 3-95-age range are now available that include appropriate age-dependent lower limits of normal. They can be applied globally to different ethnic groups. Additional data from the Indian subcontinent and Arabic, Polynesian and Latin American countries, as well as Africa will further improve these equations in the future.
              Article 0 comments Cited 1129 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Contributors
                Jessie A Elliott
                Emer Guinan
                John V Reynolds
                Journal
                Journal ID (nlm-ta): Dis Esophagus
                Journal ID (iso-abbrev): Dis Esophagus
                Journal ID (publisher-id): dote
                Title: Diseases of the Esophagus
                Publisher: Oxford University Press
                ISSN (Print): 1120-8694
                ISSN (Electronic): 1442-2050
                Publication date Collection: March 2024
                Publication date (Electronic): 28 October 2023
                Publication date PMC-release: 28 October 2023
                Volume: 37
                Issue: 3
                Electronic Location Identifier: doad062
                Affiliations
                Trinity St. James’s Cancer Institute , Trinity College Dublin and St. James’s Hospital , Dublin, Ireland
                Trinity St. James’s Cancer Institute , Trinity College Dublin and St. James’s Hospital , Dublin, Ireland
                Trinity St. James’s Cancer Institute , Trinity College Dublin and St. James’s Hospital , Dublin, Ireland
                Author notes
                Address correspondence to: John V. Reynolds, Professor of Surgery, Trinity St. James’s Cancer Institute, Dublin 8, Ireland. Email: reynoljv@ 123456tcd.ie
                Article
                Publisher ID: doad062
                DOI: 10.1093/dote/doad062
                PMC ID: 10906714
                PubMed ID: 37899136
                SO-VID: 17de2973-cd7f-447e-9921-b005a9a2c2a3
                Copyright © © The Author(s) 2023. Published by Oxford University Press on behalf of International Society for Diseases of the Esophagus.
                License:

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Date received : 31 May 2023
                Date revision received : 28 August 2023
                Page count
                Pages: 17
                Funding
                Funded by: Irish Cancer Society, DOI 10.13039/501100001593;
                Award ID: CRDF22ELL
                Categories
                Subject: Editor's Choice
                Subject: Expert Review (BY INVITATION ONLY)
                Subject: AcademicSubjects/MED00260

                Keywords: anesthesia,cardiopulmonary exercise testing,esophageal cancer,esophagectomy,nutrition,prehabilitation,surgery
                Data availability:
                Keywords: anesthesia, cardiopulmonary exercise testing, esophageal cancer, esophagectomy, nutrition, prehabilitation, surgery

                Comments

                Comment on this article