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      A Study on the Fabrication of an Effective Natural Substance Based on Schisandra chinensis Extracted Fermentation

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          Abstract

          Purpose

          In this study, a high-efficiency Schisandra chinensis extract (SCE) produced by the fermentation of effective microorganisms (EM) was used as an antioxidant material in preparing cosmetic products.

          Subjects and Methods

          We conducted the study by extracting S. chinensis via EM fermentation to increase the efficiency. Tyrosinase inhibitory factor analysis, pH, and thermal stability were measured to verify the properties of the prepared products.

          Results

          The efficacy and whitening effects of the prepared substances were verified using tyrosinase inhibitory factor analysis. As a result, it was found that both the SCE and SCE fermentation (SCEF) exhibited high, naturally originating, antioxidation ability. In addition, the pH and thermal stability of the substances were evaluated to optimize the cosmetic fabrication conditions. In this context, as the concentration of the added extract increased, the pH value decreased. The evaluation of safety and stability indicated that the substances contained effective chemical components having antioxidant activity, suppressing skin aging, and whitening effects in a weak acid range consistent with a pH of 6.25–2.98. Furthermore, there were no safety problems with the use of the obtained products even after they had been stored for 60 days.

          Conclusion

          The SCE substance is demonstrated as a possible material for cosmetic application.

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          Most cited references42

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          Antioxidant Determinations by the Use of a Stable Free Radical

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            Fermented Foods: Definitions and Characteristics, Impact on the Gut Microbiota and Effects on Gastrointestinal Health and Disease

            Fermented foods are defined as foods or beverages produced through controlled microbial growth, and the conversion of food components through enzymatic action. In recent years, fermented foods have undergone a surge in popularity, mainly due to their proposed health benefits. The aim of this review is to define and characterise common fermented foods (kefir, kombucha, sauerkraut, tempeh, natto, miso, kimchi, sourdough bread), their mechanisms of action (including impact on the microbiota), and the evidence for effects on gastrointestinal health and disease in humans. Putative mechanisms for the impact of fermented foods on health include the potential probiotic effect of their constituent microorganisms, the fermentation-derived production of bioactive peptides, biogenic amines, and conversion of phenolic compounds to biologically active compounds, as well as the reduction of anti-nutrients. Fermented foods that have been tested in at least one randomised controlled trial (RCT) for their gastrointestinal effects were kefir, sauerkraut, natto, and sourdough bread. Despite extensive in vitro studies, there are no RCTs investigating the impact of kombucha, miso, kimchi or tempeh in gastrointestinal health. The most widely investigated fermented food is kefir, with evidence from at least one RCT suggesting beneficial effects in both lactose malabsorption and Helicobacter pylori eradication. In summary, there is very limited clinical evidence for the effectiveness of most fermented foods in gastrointestinal health and disease. Given the convincing in vitro findings, clinical high-quality trials investigating the health benefits of fermented foods are warranted.
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              Fermentation-induced changes in the nutritional value of native or germinated rye

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                Author and article information

                Journal
                Clin Cosmet Investig Dermatol
                Clin Cosmet Investig Dermatol
                ccid
                Clinical, Cosmetic and Investigational Dermatology
                Dove
                1178-7015
                02 November 2021
                2021
                : 14
                : 1603-1612
                Affiliations
                [1 ]Department of Materials Technology, Faculty of Applied Sciences, Ho Chi Minh City University of Technology and Education , Ho Chi Minh City, 700000, Viet Nam
                [2 ]Department of Physical Therapy, Daegu Health College , Daegu, 41453, Republic of Korea
                [3 ]School of Mechanical Engineering, Hanoi University of Science and Technology , Ha Noi, 100000, Viet Nam
                [4 ]Department of Nano Convergence Engineering, Polymer Materials Fusion Research Center, Jeonbuk National University , Jeonju, Jeonbuk, 54896, Republic of Korea
                [5 ]Department of Beauty-Therapy & Make Up, Seokyeong University , Seoul, 02713, Republic of Korea
                Author notes
                Correspondence: Hun Jeong; Eun Sook Kim Email feerself@jbnu.ac.kr; poshop99@skuniv.ac.kr
                Author information
                http://orcid.org/0000-0003-3638-9903
                Article
                336280
                10.2147/CCID.S336280
                8576409
                1888d7a1-ad1d-48ec-82e1-345bf20200ad
                © 2021 Nguyen et al.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 27 August 2021
                : 07 October 2021
                Page count
                Figures: 3, Tables: 8, References: 42, Pages: 10
                Categories
                Original Research

                Dermatology
                schisandra chinensis,effective microorganisms fermentation,antioxidation
                Dermatology
                schisandra chinensis, effective microorganisms fermentation, antioxidation

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