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      Multisystem Inflammatory Syndrome in Children (MIS-C) During SARS-CoV-2 Delta and Omicron Variant Circulation— United States, July 2021 – January 2022

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          Abstract

          We describe 2,116 multisystem inflammatory syndrome in children (MIS-C) cases reported to CDC during Delta and Omicron circulation from July 2021–January 2022. Half of MIS-C patients were aged 5-11 years, 52% received ICU-level care, and 1.1% died. Only 3.0% of eligible patients were fully vaccinated prior to MIS-C onset.

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          Author and article information

          Contributors
          Journal
          Clin Infect Dis
          Clin Infect Dis
          cid
          Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
          Oxford University Press
          1058-4838
          1537-6591
          10 June 2022
          10 June 2022
          : ciac471
          Affiliations
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          Epidemic Intelligence Service, Centers for Disease Control and Prevention , Atlanta, GA, USA
          Northwest Portland Area Indian Health Board , Portland, OR, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          Children’s Healthcare of Atlanta, Emory University School of Medicine , Atlanta, GA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          CDC COVID-19 Response Team, Centers for Disease Control and Prevention , Atlanta, GA, USA
          Author notes
          Corresponding author: Allison Miller Centers for Disease Control and Prevention 1600 Clifton Road NE Atlanta, GA 30329 United States amiller8@ 123456cdc.gov 404-718-6309
          Article
          ciac471
          10.1093/cid/ciac471
          9214171
          35684958
          18b3eadc-db15-4aa8-a344-c65ea1624821
          © Published by Oxford University Press on behalf of Infectious Diseases Society of America 2022.

          This work is written by (a) US Government employee(s) and is in the public domain in the US.

          This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

          History
          : 03 April 2022
          : 01 June 2022
          : 03 June 2022
          Page count
          Pages: 12
          Categories
          Vaccines, Variants, and Vigilance Supplement
          AcademicSubjects/MED00290
          Custom metadata
          accepted-manuscript
          PAP

          Infectious disease & Microbiology
          multisystem inflammatory syndrome in children,covid-19,child,epidemiology

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