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      Transfer of passive immunity and serum proteinogram in the first six months of life of Criollo Lageano and black and white holstein calves Translated title: Transferência de imunidade passiva e proteinograma sérico de bezerros das raças Crioula lageana e Holandesa preta e branca nos primeiros seis meses de vida

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          Abstract

          The objective of this study was to evaluate and compare the transfer of passive immunity and the proteinogram in Criollo Lageano (CL) and Black and White Holstein (BWH) calves. Two groups were utilized with 13 Criollo Lageano and 10 BWH calves. Blood samples were collected for the measurement of total serum protein, electrophoresis of serum proteins, activity of the gamma glutamyl transferase, and concentration of IgG by the method of the zinc sulfate turbidity in periods between 24 and 36 hours of life, 15, 30, 60, 90, 120, 150 and 180 days. Statistical analysis was performed by ANOVA and Tukey test at 5% significance level, and correlations between variables were calculated. Variations of serum proteins followed a pattern of physiological behavior over the first six months of life and production of immunoglobulins was active earlier in BWH calves and slower in the Criollo Lageano, without causing any impact on their health. Gamma globulin in the first days of life (24-36h) was correlated with IgG (r=0.87 for CL and r=0.89 for BWH), PTS (r=0.91 for CL and r=0.92 for BWH), Glob (r=0.99 for CL and r=0.98 for BWH) and GGT (r=0.14 for CL and r=0.83 for BWH). It was concluded that there was no failure in the transfer of passive immunity in Criollo Lageano calves but this failure occurred in the BWH calves. IgG values estimated by the zinc sulfate turbidity and serum proteins were considered good indicators of the transfer of passive immunity in calves between 24 and 36 hours of life.

          Translated abstract

          O objetivo do presente trabalho foi verificar e comparar a transferência de imunidade passiva e o proteinograma em bezerros da raça Crioula Lageana (CL) e Holandesa Preta e Branca (HPB). Foram utilizados dois grupos sendo 13 bezerros da raça Crioula Lageana e 10 da raça HPB. Amostras de sangue foram colhidas para a mensuração da proteína sérica total, eletroforese das proteínas séricas, atividade da gama-glutamiltransferase e concentração de IgG pelo método de turvação pelo sulfato de zinco nos períodos entre 24 e 36 horas de vida, 15, 30, 60, 90, 120, 150 e 180 dias. A análise estatística foi realizada pelo teste de ANOVA e Tukey ao nível de 5% de significância, e correlações entre as variáveis. As variações das proteínas séricas obedeceram a um padrão de comportamento fisiológico ao longo dos seis primeiros meses de vida e a produção ativa de imunoglobulinas foi mais precoce nos bezerros da raça Holandesa e mais lenta nos da raça Crioula Lageana, sem provocar qualquer impacto sobre a saúde dos mesmos. A gamaglobulina no primeiro dia de vida (24-36h) correlacionou-se com a IgG (r=0,87 CL e r=0,89 HPB), PTS (r=0,91 CL e r=0,92 HPB), Glob (r=0,99 CL e r=0,98) e GGT (r=0,14 CL e r=0,83 HPB). Conclui-se que não houve falha na transferência de imunidade passiva nos bezerros da raça Crioula Lageana e falha na raça Holandesa Preta e Branca. Os valores de IgG estimados pelo método da turvação pelo sulfato de zinco e das proteínas séricas foram bons indicadores da transferência de imunidade passiva nos bezerros entre 24 e 36 horas de vida.

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          Most cited references58

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          Essentials of Veterinary Hematology

          Essentials of Veterinary Hematology is a concise text on the subject of veterinary hematology. It has been written to provide a ready source of current and fundamental information necessary to the understanding of basic concepts in hematology as a discipline and veterinary hematology as a specialty.<br><br>The book is aimed at undergraduate veterinary students, veterinary medical technologists, animal technicians, and all those interested in an abridged text in comparative hematology. Graduate veterinary students can use it as a ready source for reviewing the pathophysiology of blood as it relates to clinical veterinary medicine. A generalized approach to the interpretation of various hematologic abnormalities is presented throughout the text, along with comments on species-specific hematologic attributes and hematologic abnormalities encountered in various species.
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            A kinetic photometric method for serum gamma-glutamyl transpeptidase.

            G Szasz (1969)
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              Associations between passive immunity and morbidity and mortality in dairy heifers in Florida, USA

              A prospective cohort study was undertaken to determine calf-level factors that affected calf health status between birth and 6 months of age. A convenience sample of approximately 3300 female Holstein calves born in 1991 on two large Florida dairy farms was used for the study. Data collected on each calf at birth included farm of origin, weight, height at the pelvis, birth date, and serum total protein (a measure of colostral immunoglobulin absorption). Birth season was dichotomized into summer and winter using meteorological data collected by University of Florida Agricultural Research Stations. Health data including date of initial treatment and number of treatments were collected for the diseases diarrhea, omphalitis, septicemia and pneumonia. All calves were followed for 6 months. Cumulative incidences of mortality and occurrence of diarrhea, omphalitis, septicemia and pneumonia were 0.12, 0.35, 0.11, 0.24 and 0.21, respectively. Serum total protein (TP) was a significant risk factor for mortality. The association of TP and mortality was quadratic and showed a dramatic decrease in mortality as TP increased from 4.0 to 5.0 g/dl, a small improvement from 5.0 to 6.0 g/dl and virtually no improvement in mortality rates as TP increased over 6.0 g/dl. The hazard mortality ratio was constant from birth to six months, indicating that the increased risk of mortality associated with low levels of TP was evident through six months of age. No interactions between TP, farm, season, or birth weight were found in these analyses. Serum total protein concentration was a significant risk factor for the occurrences, age of onset and severity of septicemia and pneumonia. The association between TP and septicemia was linear and an interaction with birth season was found. The association between TP and pneumonia was quadratic, and in contrast to the TP-and-septicemia relationship, the morbidity hazard ratio for pneumonia was not constant over the time measured; that is, colostral immunity protected the calf from developing pneumonia early in life, but this effect disappeared as the calf got older. Total protein was not a significant risk factor for diarrhea or omphalitis.
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                Author and article information

                Journal
                pvb
                Pesquisa Veterinária Brasileira
                Pesq. Vet. Bras.
                Colégio Brasileiro de Patologia Animal - CBPA (Rio de Janeiro, RJ, Brazil )
                0100-736X
                1678-5150
                October 2012
                : 32
                : 10
                : 980-986
                Affiliations
                [01] Lages SC orgnameUniversidade do Estado de Santa Catarina orgdiv1Centro de Ciências Agroveterinárias orgdiv2Departamento de Medicina Veterinária Brazil
                [02] Lages SC orgnameCentro Universitário Facvest Brazil
                [03] Brasília DF orgnameEmbrapa Recursos Genéticos e Biotecnologia Brazil
                [05] Lages SC orgnameUDESC orgdiv1CAV orgdiv2Departamento de Medicina Veterinária
                [04] Campo Grande MS orgnameEmbrapa Gado de Corte Brazil
                Article
                S0100-736X2012001000005 S0100-736X(12)03201005
                18b477d0-c688-47a7-acf7-28a705a83ffb

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 25 June 2012
                : 15 February 2012
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 68, Pages: 7
                Product

                SciELO Brazil

                Categories
                Livestock Diseases

                Imunoglobulinas,Immunoglobulins,bovine,serum proteins,native breeds,bovino,proteínas séricas,raças nativas

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