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      Eucalyptol alleviates inflammation and pain responses in a mouse model of gout arthritis

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          Abstract

          <p class="first" id="d19534437e145">Gout arthritis, which is provoked by monosodium urate (MSU) crystal accumulation in the joint and periarticular tissues, induces severe pain and affects quality of life of the patients. Eucalyptol (1,8-cineol), the principal component in the essential oils of eucalyptus leaves, is known to possess anti-inflammatory and analgesic properties. We aimed to examine the therapeutic effects of eucalyptol on gout arthritis and related mechanisms. </p>

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          Author and article information

          Contributors
          Journal
          British Journal of Pharmacology
          Br J Pharmacol
          Wiley
          0007-1188
          1476-5381
          May 2020
          February 12 2020
          May 2020
          : 177
          : 9
          : 2042-2057
          Affiliations
          [1 ]Department of Neurobiology and Acupuncture ResearchThe Third Clinical Medical College, Zhejiang Chinese Medical University, Key Laboratory of Acupuncture and Neurology of Zhejiang Province Hangzhou China
          [2 ]Department of Pathology, School of Basic Medical ScienceZhejiang Chinese Medical University Hangzhou China
          [3 ]Academy of Chinese Medical SciencesZhejiang Chinese Medical University Hangzhou China
          [4 ]Department of PharmacologyHebei Medical University Shijiazhuang China
          Article
          10.1111/bph.14967
          7161556
          31883118
          1b7b155d-3ff7-4703-90c4-8a5f258069ee
          © 2020

          http://onlinelibrary.wiley.com/termsAndConditions#vor

          http://doi.wiley.com/10.1002/tdm_license_1.1

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