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      Penetration of Doxycycline into the Aqueous Humor from Blood

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          Abstract

          25 human subjects of both sexes undergoing operations for senile cataract were selected for the present study. Doxycycline was administered orally at various intervals to assess its penetration in the aqueous humor through systemic absorption from blood. It was concluded that at the usually recommended dose schedule, doxycycline may serve as a general prophylactic, but not as one which offers a blanket cover against all the pathogenic micro-organisms.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1981
          1981
          04 December 2009
          : 13
          : 4
          : 194-197
          Affiliations
          aDepartment of Pharmacology, and bUpgraded Department of Opthalmology, S.M.S. Medical College, Jaipur, India; cFaculty of Medicine, Al-Fateh University, Tripoli, Libya
          Article
          265148 Ophthalmic Res 1981;13:194–197
          10.1159/000265148
          © 1981 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Original Paper

          Vision sciences, Ophthalmology & Optometry, Pathology

          Antibiotics, Prophylactic treatment, Doxycycline

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