Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Background

Pedigree or purebred dogs are often stated to have high prevalence of disorders which are commonly assumed to be a consequence of inbreeding and selection for exaggerated features. However, few studies empirically report and rank the prevalence of disorders across breeds although such data are of critical importance in the prioritisation of multiple health concerns, and to provide a baseline against which to explore changes over time. This paper reports an owner survey that gathered disorder information on Kennel Club registered pedigree dogs, regardless of whether these disorders received veterinary care. This study aimed to determine the prevalence of disorders among pedigree dogs overall and, where possible, determine any variation among breeds.

Results

This study included morbidity data on 43,005 live dogs registered with the Kennel Club. Just under two thirds of live dogs had no reported diseases/conditions. The most prevalent diseases/conditions overall were lipoma (4.3%; 95% confidence interval 4.13-4.52%), skin (cutaneous) cyst (3.1%; 2.94-3.27%) and hypersensitivity (allergic) skin disorder (2.7%; 2.52-2.82%). For the most common disorders in the most represented breeds, 90 significant differences between the within breed prevalence and the overall prevalence are reported.

Conclusion

The results from this study have added vital epidemiological data on disorders in UK dogs. It is anticipated that these results will contribute to the forthcoming Breed Health & Conservation Plans, a Kennel Club initiative aiming to assist in the identification and prioritisation of breeding selection objectives for health and provide advice to breeders/owners regarding steps that may be taken to minimise the risk of the disease/disorders. Future breed-specific studies are recommended to report more precise prevalence estimates within more breeds.

Electronic supplementary material

The online version of this article (doi:10.1186/s40575-017-0047-3) contains supplementary material, which is available to authorized users.

Related collections

Most cited references 38

Record: found
Abstract: found
Article: not found

Answering autobiographical questions: the impact of memory and inference on surveys.

N. BRADBURN, L J Rips, S K Shevell (1987)

Survey questions often probe respondents for quantitative facts about events in their past: "During the last 2 weeks, on days when you drank liquor, about how many drinks did you have?" "During the past 12 months, how many visits did you make to a dentist?" "When did you last work at a full-time job?" are all examples from national surveys. Although questions like these make an implicit demand to remember and enumerate specific autobiographical episodes, respondents frequently have trouble complying because of limits on their ability to recall. In these situations, respondents resort to inferences that use partial information from memory to construct a numeric answer. Results from cognitive psychology can be useful in understanding and investigating these phenomena. In particular, cognitive research can help in identifying situations that inhibit or facilitate recall and can reveal inferences that affect the accuracy of respondents' answers.

0 comments Cited 203 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Mortality in north american dogs from 1984 to 2004: an investigation into age-, size-, and breed-related causes of death.

J. Fleming, K Creevy, D E L Promislow (2015)

Anecdotal beliefs and limited research suggest variable patterns of mortality in age, size, and breed cohorts of dogs. Detailed knowledge of mortality patterns would facilitate development of tailored health-maintenance practices and contribute to the understanding of the genetic basis of disease. To describe breed-specific causes of death in all instances of canine mortality recorded in the Veterinary Medical Database (VMDB)(a) between 1984 and 2004. We hypothesized that causes of death, categorized by organ system (OS) or pathophysiologic process (PP), would segregate by age, body mass, and breed. 74,556 dogs from the VMDB for which death was the outcome of the recorded hospital visit. Retrospective study. Causes of death from abstracted VMDB medical records were categorized by OS and PP and analyzed by age, breed, and breed-standard mass of dog. Causes of death, categorized by OS or PP, segregated by age, breed, and breed-standard mass. Young dogs died more commonly of gastrointestinal and infectious causes whereas older dogs died of neurologic and neoplastic causes. Increasing age was associated with an increasing risk of death because of cardiovascular, endocrine, and urogenital causes, but not because of hematopoietic or musculoskeletal causes. Dogs of larger breeds died more commonly of musculoskeletal and gastrointestinal causes whereas dogs of smaller breeds died more commonly of endocrine causes. Not all causes of death contribute equally to mortality within age, size, or breed cohorts. Documented patterns now provide multiple targets for clinical research and intervention. Copyright © 2011 by the American College of Veterinary Internal Medicine.

0 comments Cited 139 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: not found
Article: not found

Inherited defects in pedigree dogs. Part 1: disorders related to breed standards.

Lucy Asher, Gillian Diesel, Jennifer F Summers … (2009)

The United Kingdom pedigree-dog industry has faced criticism because certain aspects of dog conformation stipulated in the UK Kennel Club breed standards have a detrimental impact on dog welfare. A review of conformation-related disorders was carried out in the top 50 UK Kennel Club registered breeds using systematic searches of existing information. A novel index to score severity of disorders along a single scale was also developed and used to conduct statistical analyses to determine the factors affecting reported breed predisposition to defects. According to the literature searched, each of the top 50 breeds was found to have at least one aspect of its conformation predisposing it to a disorder; and 84 disorders were either directly or indirectly associated with conformation. The Miniature poodle, Bulldog, Pug and Basset hound had most associations with conformation-related disorders. Further research on prevalence and severity is required to assess the impact of different disorders on the welfare of affected breeds.

0 comments Cited 105 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Contributors

B. M. Wiles:

ORCID: http://orcid.org/0000-0001-5123-7989

Bonnie.Wiles@thekennelclub.org.uk

A. M. Llewellyn-Zaidi: Aimee.Llewellyn-Zaidi@ipfdogs.com

K.M. Evans: Katy.Evans@thekennelclub.org.uk

D. G. O’Neill: doneill@rvc.ac.uk

T. W. Lewis: Tom.Lewis@thekennelclub.org.uk

Journal

Journal ID (nlm-ta): Canine Genet Epidemiol

Journal ID (iso-abbrev): Canine Genet Epidemiol

Title: Canine Genetics and Epidemiology

Publisher: BioMed Central (London )

ISSN (Electronic): 2052-6687

Publication date (Electronic): 19 September 2017

Publication date PMC-release: 19 September 2017

Publication date Collection: 2017

Volume: 4

Electronic Location Identifier: 8

Affiliations

[1 ]The Kennel Club, Clarges Street, London, W1J 8AB England, UK

[2 ]International Partnership for Dogs, 504547 Grey Rd 1, Georgia Bluffs, ON England, UK

[3 ]School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire, LE12 5RD England, UK

[4 ]ISNI 0000 0004 0425 573X, GRID grid.20931.39, Veterinary Epidemiology, Economics and Public Health, , Royal Veterinary College, ; London, NW1 0TU UK

Author information

B. M. Wiles http://orcid.org/0000-0001-5123-7989

Article

Publisher ID: 47

DOI: 10.1186/s40575-017-0047-3

PMC ID: 5604186

PubMed ID: 28932406

SO-VID: 1cc3882f-82fb-4624-897d-bdda77dc7036

License:

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

History

Date received : 10 October 2016

Date accepted : 29 June 2017

Custom metadata

Keywords: prevalence,morbidity,dogs,survey,breeds,pedigree

Data availability:

Keywords: prevalence, morbidity, dogs, survey, breeds, pedigree

Comments

Comment on this article

scite_

Cited by 21

See all cited by

Most referenced authors 485

See all reference authors

- Version 1
- Version 1

Large-scale survey to estimate the prevalence of disorders for 192 Kennel Club registered breeds

Read this article at

Abstract

Background

Results

Conclusion

Electronic supplementary material

Related collections

Parasite

Most cited references 38

Answering autobiographical questions: the impact of memory and inference on surveys.

Mortality in north american dogs from 1984 to 2004: an investigation into age-, size-, and breed-related causes of death.

Inherited defects in pedigree dogs. Part 1: disorders related to breed standards.

Author and article information

Contributors

Journal

Affiliations

Author information

Article

History

Categories

Custom metadata

Comments

Comment on this article

Similar content 131

Cited by 21

Most referenced authors 485