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      Introduction to macroporous cryogels.

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          Abstract

          Cryogels are highly elastic three-dimensional materials consisting of a network of interconnected macropores. This unique morphology combined with high mechanical and chemical stability provides excellent mass flow properties. The matrices are synthesized at subzero temperatures from almost any gel-forming precursor. The main fields of application are in biotechnology as 3D-scaffold for cell cultivation, and tissue engineering, or bioseparation as chromatographic media for the separation and purification of biomolecules. This chapter briefly highlights the preparation, properties, and application of these materials.

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          Author and article information

          Journal
          Methods Mol Biol
          Methods in molecular biology (Clifton, N.J.)
          Springer Science and Business Media LLC
          1940-6029
          1064-3745
          2015
          : 1286
          Affiliations
          [1 ] Leibniz-Institut für Oberflächenmodifizierung, Permoserstraße 15, Leipzig, 04318, Germany, senta.reichelt@iom-leipzig.de.
          Article
          10.1007/978-1-4939-2447-9_14
          25749954
          1d70488c-b8e5-4797-be87-d34b82df8a77
          History

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