Gargling with Ketamine Attenuates the Postoperative Sore Throat

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Summary

Postoperative sore throat (POST) is a common complication of anaesthesia with endotracheal tube that affects patient satisfaction after surgery. Therefore, this complication remains to be resolved in patients undergoing endotracheal intubation. The aim of the study was to compare the effectiveness of ketamine gargles with placebo in preventing POST after endotracheal intubation. Forty patients scheduled for elective surgery under general anaesthesia were randomized into: Group C, water 30 ml; Group K, ketamine 50 mg in water 29 ml. Patients were asked to gargle this mixture for 40 seconds, 5 minutes before induction of anaesthesia. POST was graded at 4, 8 and 24 hours after operation on a four-point scale (0-3). In the Control group POST occurred more frequently, when compared with patients belonging to Ketamine group, at 4, 8, and 24 hours and significantly more patients suffered severe POST in Control group at 8 and 24 hours compared with Ketamine group ( P<0.05). We demonstrated that gargling with ketamine significantly attenuated POST, with no drug-related side effects were observed.

Related collections

Most cited references 30

Record: found
Abstract: found
Article: not found

Which clinical anesthesia outcomes are important to avoid? The perspective of patients.

M Weinger, Chong A. Kim, S Carney … (1999)

Healthcare quality can be improved by eliciting patient preferences and customizing care to meet the needs of the patient. The goal of this study was to quantify patients' preferences for postoperative anesthesia outcomes. One hundred one patients in the preoperative clinic completed a written survey. Patients were asked to rank (order) 10 possible postoperative outcomes from their most undesirable to their least undesirable outcome. Each outcome was described in simple language. Patients were also asked to distribute $100 among the 10 outcomes, proportionally more money being allocated to the more undesirable outcomes. The dollar allocations were used to determine the relative value of each outcome. Rankings and relative value scores correlated closely (r2 = 0.69). Patients rated from most undesirable to least undesirable (in order): vomiting, gagging on the tracheal tube, incisional pain, nausea, recall without pain, residual weakness, shivering, sore throat, and somnolence (F-test < 0.01). Although there is variability in how patients rated postoperative outcomes, avoiding nausea/vomiting, incisional pain, and gagging on the endotracheal tube was a high priority for most patients. Whether clinicians can improve the quality of anesthesia by designing anesthesia regimens that most closely meet each individual patient's preferences for clinical outcomes deserves further study.

0 comments Cited 138 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Postoperative sore throat: cause, prevention and treatment.

F McHardy, F Chung (1999)

Sore throat is a common postoperative complaint, occurring most often following tracheal intubation. Factors such as tracheal-tube size and cuff design have been shown to be important causative factors. Routine tracheal intubation for elective surgical procedures can result in pathological changes, trauma and nerve damage which may also account for postoperative throat symptoms. Sore throat following the use of a laryngeal mask appears to be related to the technique of insertion but the contribution of intracuff pressure remains to be clarified. It would appear, however, that high intracuff pressure is associated with nerve palsies due to neuropraxia and nerve compression. Careful insertion techniques for both the tracheal tube and laryngeal mask are of paramount importance in the prevention of airway trauma and postoperative sore throat.

0 comments Cited 111 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: not found
Article: not found

Correlation of endotracheal tube size with sore throat and hoarseness following general anesthesia.

B Cullen, Kyle Bishop, Matthew D. Stout … (1987)

0 comments Cited 59 times – based on 0 reviews      Review now

Bookmark

All references

Author and article information

Journal

Journal ID (nlm-ta): Indian J Anaesth

Journal ID (publisher-id): IJA

Title: Indian Journal of Anaesthesia

Publisher: Medknow Publications (India )

ISSN (Print): 0019-5049

ISSN (Electronic): 0976-2817

Publication date (Print): February 2009

Volume: 53

Issue: 1

Pages: 40-43

Affiliations

[1 ]Consultant Anaesthesiologist, Kolkata

[2 ]Assistant Professor of Anaesthesiology, Medical College & Hospital, Kolkata

[3 ]DNB Student, Apollo Gleneagles Hospital, Kolkata

Author notes

Correspondence to: A Rudra, 1, Shibnarayan Das Lane, Kolkata – 700006. E mail: sumanc_24@ 123456yahoo.co.in

Article

Publisher ID: IJA-53-40

PMC ID: 2900032

PubMed ID: 20640076

SO-VID: 1db5d2eb-11f6-427e-8d49-238ab09981ee

License:

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Gargling with Ketamine Attenuates the Postoperative Sore Throat

Read this article at

Abstract

Summary

Related collections

Cardiovascular Innovations and Applications

Most cited references 30

Which clinical anesthesia outcomes are important to avoid? The perspective of patients.

Postoperative sore throat: cause, prevention and treatment.

Correlation of endotracheal tube size with sore throat and hoarseness following general anesthesia.

Author and article information

Journal

Affiliations

Author notes

Article

History

Categories

Comments

Comment on this article

Similar content 284

Cited by 23

Most referenced authors 186