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      How to calculate sample size in animal studies?

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          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Calculation of sample size is one of the important component of design of any research including animal studies. If a researcher select less number of animals it may lead to missing of any significant difference even if it exist in population and if more number of animals selected then it may lead to unnecessary wastage of resources and may lead to ethical issues. In this article, on the basis of review of literature done by us we suggested few methods of sample size calculations for animal studies.

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          Most cited references 14

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          G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences.

          G*Power (Erdfelder, Faul, & Buchner, 1996) was designed as a general stand-alone power analysis program for statistical tests commonly used in social and behavioral research. G*Power 3 is a major extension of, and improvement over, the previous versions. It runs on widely used computer platforms (i.e., Windows XP, Windows Vista, and Mac OS X 10.4) and covers many different statistical tests of the t, F, and chi2 test families. In addition, it includes power analyses for z tests and some exact tests. G*Power 3 provides improved effect size calculators and graphic options, supports both distribution-based and design-based input modes, and offers all types of power analyses in which users might be interested. Like its predecessors, G*Power 3 is free.
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            The Family of Ln2Ti2S2O5 Compounds (Ln=Nd Sm Gd Tb Dy Ho Er and Y) Optical Properties

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              Statsitical Power Analysis for the Behavioral Sciences

               J Cohen,  JL Cohen,  JM Cohen (1988)
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                Author and article information

                Journal
                J Pharmacol Pharmacother
                J Pharmacol Pharmacother
                JPP
                Journal of Pharmacology & Pharmacotherapeutics
                Medknow Publications & Media Pvt Ltd (India )
                0976-500X
                0976-5018
                Oct-Dec 2013
                : 4
                : 4
                : 303-306
                Affiliations
                Department of Pharmacology, GMERS Medical College, Patan, Government Medical College, Surat, Gujarat, India
                Author notes
                Address for correspondence: Jaykaran Charan, Department of Pharmacology, Government Medical College, Surat, Gujarat, India. E-mail: drjaykaran@ 123456yahoo.co.in
                JPP-4-303
                10.4103/0976-500X.119726
                3826013
                24250214
                Copyright: © Journal of Pharmacology and Pharmacotherapeutics

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                Categories
                Educational Forum

                Pharmacology & Pharmaceutical medicine

                alpha error, sample size, power, animal studies

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