Two new species of Dendrophthora Eichler (Viscaceae) from northwestern Venezuela are described and illustrated. Both mistletoes, D. apiculata Canelón et al., sp. nov. and D. coronata Canelón et al., sp. nov., are confined to subpáramo and páramo ecosystems of the Venezuelan Andes and are, at present, only known from Guaramacal National Park (Portuguesa and Trujillo states). Ecological aspects and possible taxonomic affinities are discussed. A distribution map also is presented.