2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      New perspectives on how to formulate alcohol drinking guidelines

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Background

          Low‐Risk Alcohol Drinking Guidelines (LRDGs) aim to reduce the harms caused by alcohol. However, considerable discrepancies exist in the ‘low‐risk’ thresholds employed by different countries.

          Argument/analysis

          Drawing upon Canada's LRDGs update process, the current paper offers the following propositions for debate regarding the establishment of ‘low‐risk’ thresholds in national guidelines: (1) as an indicator of health loss, years of life lost (YLL) has several advantages that could make it more suitable for setting guidelines than deaths, premature deaths or disability adjusted years of life (DALYs) lost. (2) Presenting age‐specific guidelines may not be the most appropriate way of providing LRDGs. (3) Given past overemphasis on the so‐called protective effects of alcohol on health, presenting cause‐specific guidelines may not be appropriate compared with a ‘whole health’ effect derived from a weighted composite risk function comprising conditions that are causally related to alcohol consumption. (4) To help people reduce their alcohol use, presenting different risk zones associated with alcohol consumption instead of a single low risk threshold may be advantageous.

          Conclusions

          National LRDGs should be based on years of life lost and should be neither age‐specific nor cause‐specific. We recommend using risk zones rather than a single drinking threshold to help people assess their own risk and encourage the adoption of behaviours with positive health impacts across the alcohol use spectrum.

          Related collections

          Most cited references60

          • Record: found
          • Abstract: not found
          • Book: not found

          Diagnostic and Statistical Manual of Mental Disorders

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            GRADE: an emerging consensus on rating quality of evidence and strength of recommendations.

              Bookmark
              • Record: found
              • Abstract: found
              • Article: found
              Is Open Access

              Alcohol consumption and site-specific cancer risk: a comprehensive dose–response meta-analysis

              Background: Alcohol is a risk factor for cancer of the oral cavity, pharynx, oesophagus, colorectum, liver, larynx and female breast, whereas its impact on other cancers remains controversial. Methods: We investigated the effect of alcohol on 23 cancer types through a meta-analytic approach. We used dose–response meta-regression models and investigated potential sources of heterogeneity. Results: A total of 572 studies, including 486 538 cancer cases, were identified. Relative risks (RRs) for heavy drinkers compared with nondrinkers and occasional drinkers were 5.13 for oral and pharyngeal cancer, 4.95 for oesophageal squamous cell carcinoma, 1.44 for colorectal, 2.65 for laryngeal and 1.61 for breast cancer; for those neoplasms there was a clear dose–risk relationship. Heavy drinkers also had a significantly higher risk of cancer of the stomach (RR 1.21), liver (2.07), gallbladder (2.64), pancreas (1.19) and lung (1.15). There was indication of a positive association between alcohol consumption and risk of melanoma and prostate cancer. Alcohol consumption and risk of Hodgkin's and Non-Hodgkin's lymphomas were inversely associated. Conclusions: Alcohol increases risk of cancer of oral cavity and pharynx, oesophagus, colorectum, liver, larynx and female breast. There is accumulating evidence that alcohol drinking is associated with some other cancers such as pancreas and prostate cancer and melanoma.
                Bookmark

                Author and article information

                Contributors
                Journal
                Addiction
                Addiction
                Wiley
                0965-2140
                1360-0443
                September 08 2023
                Affiliations
                [1 ] Institute for Mental Health Policy Research, Campbell Family Mental Health Research Institute Centre for Addiction and Mental Health Toronto Ontario Canada
                [2 ] Dalla Lana School of Public Health University of Toronto Toronto Ontario Canada
                [3 ] Canadian Centre on Substance Use and Addiction Ottawa Ontario Canada
                [4 ] College of Medicine University of Saskatchewan Saskatoon Saskatchewan Canada
                [5 ] Canadian Institute for Substance Use Research University of Victoria Victoria British Columbia Canada
                [6 ] Department of Community Health and Epidemiology, Department of Emergency Medicine Dalhousie University Halifax Nova Scotia Canada
                [7 ] Department of Family Medicine University of Ottawa Ottawa Ontario Canada
                [8 ] Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry Western University London Ontario Canada
                [9 ] Centre of Excellence for Women's Health Vancouver British Columbia Canada
                [10 ] Department of Health and Wellness Government of Nova Scotia Halifax Nova Scotia Canada
                [11 ] Public Health Ontario Toronto Ontario Canada
                [12 ] Department of Psychology St Francis Xavier University Antigonish Nova Scotia Canada
                [13 ] Gambling Research Exchange Ontario Guelph Ontario Canada
                Article
                10.1111/add.16316
                37680111
                22c8859b-2de2-4961-b2d0-364b36c4b606
                © 2023

                http://onlinelibrary.wiley.com/termsAndConditions#vor

                History

                Comments

                Comment on this article