Dose uncertainties in IMPT for oropharyngeal cancer in the presence of anatomical, range, and setup errors.

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Abstract

Setup, range, and anatomical uncertainties influence the dose delivered with intensity modulated proton therapy (IMPT), but clinical quantification of these errors for oropharyngeal cancer is lacking. We quantified these factors and investigated treatment fidelity, that is, robustness, as influenced by adaptive planning and by applying more beam directions.

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Journal

Journal ID (iso-abbrev): Int. J. Radiat. Oncol. Biol. Phys.

Title: International journal of radiation oncology, biology, physics

ISSN (Electronic): 1879-355X

ISSN (Print): 0360-3016

Publication date (Electronic): Dec 1 2013

Volume: 87

Issue: 5

Affiliations

[1 ] Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands. Electronic address: aafke.kraan@pi.infn.it.

[2 ] Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.

[3 ] Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

Article

Publisher Item ID: S0360-3016(13)03101-5

DOI: 10.1016/j.ijrobp.2013.09.014

PubMed ID: 24351409

SO-VID: 2462213d-c2c3-4747-9319-bfc0c930e381

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