Swallowing sparing intensity modulated radiotherapy (SW-IMRT) in head and neck cancer: Clinical validation according to the model-based approach.

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Abstract

The aim of this study was to clinically validate a multivariable normal tissue complication probability (NTCP) model for grade 2-4 swallowing dysfunction at 6months after radiotherapy or chemoradiation (SWALM6) in head and neck cancer patients treated with swallowing sparing intensity modulated radiotherapy (SW-IMRT) and to test if SW-IMRT resulted in a reduction of the prevalence of SWALM6.

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Journal

Journal ID (iso-abbrev): Radiother Oncol

Title: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

ISSN (Electronic): 1879-0887

ISSN (Print): 0167-8140

Publication date (Electronic): Feb 2016

Volume: 118

Issue: 2

Affiliations

[1 ] Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, The Netherlands.

[2 ] Department of Otorhinolaryngology-Head and Neck Surgery, VU University Medical Center Amsterdam, The Netherlands.

[3 ] Department of Radiation Oncology, VU University Medical Center Amsterdam, The Netherlands.

[4 ] Department of Medical Oncology, University of Groningen, University Medical Center Groningen, The Netherlands.

[5 ] Department of Otorhinolaryngology-Head and Neck Surgery, University of Groningen, University Medical Center Groningen, The Netherlands.

[6 ] Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, The Netherlands.

[7 ] Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, The Netherlands. Electronic address: j.a.langendijk@umcg.nl.

Article

Publisher Item ID: S0167-8140(15)00613-1

DOI: 10.1016/j.radonc.2015.11.009

PubMed ID: 26700602

SO-VID: 277ae05a-6384-444e-859d-f189dcbeb6a3

History

Keywords: Head and neck cancer,Model based approach,Radiotherapy,Swallowing sparing IMRT

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Keywords: Head and neck cancer, Model based approach, Radiotherapy, Swallowing sparing IMRT

Swallowing sparing intensity modulated radiotherapy (SW-IMRT) in head and neck cancer: Clinical validation according to the model-based approach.

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Karger: Oncology

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