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Can copeptin and troponin T ratio predict final infarct size and myocardial salvage index in patients with ST-elevation myocardial infarction: A sub-study of the DANAMI-3 trial.
Ásthildur Árnadóttir
1 ,
Mikkel Schoos
2 ,
Jacob Lønborg
2 ,
Kiril Ahtarovski
2 ,
Henning Kelbæk
3 ,
Steffen Helqvist
2 ,
Dan Høfsten
2 ,
Peter Clemmensen
4 ,
Thomas Engstrøm
2 ,
Lars Nepper-Christensen
2 ,
Niels Vejlstrup
2 ,
Lars Køber
2 ,
Kasper Iversen
5
Sep 2018
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Abstract
Primary percutaneous coronary intervention (pPCI) is recommended in patients presenting with ST-elevation myocardial infarction (STEMI) within <12 h of symptom onset. However, patients-reported symptom duration is not always reliable. Cardiac specific troponin T (cTnT) and the endogenous stress marker copeptin have different temporal release patterns for myocardial infarction MI. We hypothesized that copeptin/troponin-ratio is associated to the duration of coronary occlusion and therefore inversely proportional to myocardial salvage.