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      A phenomenological approach to diagnosing psychosis in autism spectrum disorder and intellectual disability: a case series

      case-report
      Rahul Rai, Samuel Tromans, Chaya Kapugama,   Verity Chester, Ignatius Gunaratna, Peter Langdon, Regi T. Alexander
      Advances in Autism
      Emerald Publishing Limited
      Mental health, Learning disability, Mental disorder, Schizophrenia, Autism spectrum condition, Comorbidity

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          Abstract

          Purpose

          The diagnosis of psychosis in individuals with autism spectrum disorder (ASD) poses a unique clinical challenge. The presence of intellectual disability (ID) further complicates the diagnostic picture. Reliable and timely diagnosis of psychosis in such individuals minimises the duration of untreated psychotic symptoms and the subsequent impact on the quality of life of the patients concerned. The paper aims to discuss this issue.

          Design/methodology/approach

          The authors present four patients with psychosis, ASD and ID, who have received care within forensic mental health and ID settings. These examples demonstrate the interaction between these conditions, as well as issues pertaining to diagnosis and management.

          Findings

          In all four patients, sustained use of antipsychotic medication was objectively associated with an improvement in psychotic symptoms and quality of life. In instances where autistic phenomena were accentuated upon development of psychosis, such features returned to the baseline levels evident prior to the onset of psychosis.

          Practical implications

          The discussion and related case examples could improve the understanding of the possibility of psychosis in individuals with ASD and ID, and increase awareness of this diagnostic possibility among healthcare professionals.

          Originality/value

          This is the first published case series illustrating the challenges of diagnosing psychosis in individuals with ASD and ID.

          Related collections

          Most cited references15

          • Record: found
          • Abstract: not found
          • Article: not found

          Problems of nosology and psychodynamics of early infantile autism.

          L Kanner (1949)
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            • Article: not found

            Comorbidity of Asperger syndrome: a preliminary report.

            Asperger syndrome (AS) is a pervasive developmental disorder characterized by autistic social dysfunction and idiosyncratic interests in the presence of normal intelligence. There is no history of language delay. Although people with AS are known to suffer from comorbid psychiatric conditions, few studies have systematically addressed this topic. This preliminary report describes the occurrence of psychiatric disorders in a series of patients with AS diagnosed according to the ICD-10/DSM-IV criteria. Out of 35 patients (29 males and six females; mean age 15.1 years; mean verbal IQ 105.9; mean performance IQ 97.5; mean full-scale IQ 102.7), 23 patients (65%) presented with symptoms of an additional psychiatric disorder at the time of evaluation or during the 2-year follow-up. Children were most likely to suffer from attention deficit hyperactivity disorder, while depression was the most common diagnosis in adolescents and adults. The implications of these findings are discussed.
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              Is Open Access

              Psychosis in autism: comparison of the features of both conditions in a dually affected cohort†

              Background There is limited information on the presentation and characteristics of psychotic illness experienced by people with autism spectrum disorder (ASD). Aims To describe autistic and psychotic phenomenology in a group of individuals with comorbid ASD and psychosis (ASD–P) and compare this group with populations affected by either, alone. Method We studied 116 individuals with ASD–P. We compared features of their ASD with people with ASD and no comorbid psychosis (ASD–NP), and clinical characteristics of psychosis in ASD–P with people with psychosis only. Results Individuals with ASD–P had more diagnoses of atypical psychosis and fewer of schizophrenia compared with individuals with psychosis only. People with ASD–P had fewer stereotyped interests/behaviours compared with those with ASD–NP. Conclusions Our data show there may be a specific subtype of ASD linked to comorbid psychosis. The results support findings that psychosis in people with ASD is often atypical, particularly regarding affective disturbance.
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                Author and article information

                Contributors
                Journal
                AIA
                10.1108/AIA
                Advances in Autism
                AIA
                Emerald Publishing Limited
                2056-3868
                03 April 2018
                : 4
                : 2
                : 39-48
                Affiliations
                [1]Hertfordshire Partnership NHS Foundation Trust, Colchester, UK
                [2]Leicestershire Partnership NHS Trust, Leicester, UK
                [3]Department of Health Sciences, University of Leicester , Leicester, UK
                [4]Department of Psychiatry, Partnerships in Care Learning Disability Services, St Johns House, Norfolk, UK
                [5]Norwich Medical School, University of East Anglia , Norwich, UK
                [6]Tizard Centre, University of Kent , Kent, UK
                [7]Department of Psychiatry, St Johns House, Norfolk, UK
                Author notes
                Verity Chester can be contacted at: veritychester@priorygroup.com
                Article
                608392 AIA-01-2018-0004.pdf AIA-01-2018-0004
                10.1108/AIA-01-2018-0004
                28bf23e5-95b5-4d5d-a532-d07e417c905f
                © Emerald Publishing Limited
                History
                : 29 January 2018
                : 07 March 2018
                : 07 March 2018
                Page count
                Figures: 0, Tables: 6, Equations: 0, References: 34, Pages: 10, Words: 5711
                Categories
                case-report, Case study
                cat-HSC, Health & social care
                cat-LID, Learning & intellectual disabilities
                Custom metadata
                yes
                yes
                JOURNAL
                included

                Health & Social care
                Mental health,Learning disability,Mental disorder,Schizophrenia,Autism spectrum condition,Comorbidity

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