Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

Author(s): Tyler M Seibert , Chun Chieh Fan , Yunpeng Wang , Verena Zuber , Roshan Karunamuni , J Kellogg Parsons , Rosalind A Eeles , Douglas F Easton , ZSofia Kote-Jarai , Ali Amin Al Olama , Sara Benlloch Garcia , Kenneth Muir , Henrik Grönberg , Fredrik Wiklund , Markus Aly , Johanna Schleutker , Csilla Sipeky , Teuvo LJ Tammela , Børge G Nordestgaard , Sune F Nielsen , Maren Weischer , Rasmus Bisbjerg , M Andreas Røder , Peter Iversen , Tim J Key , Ruth C Travis , David E Neal , Jenny L Donovan , Freddie C Hamdy , Paul Pharoah , Nora Pashayan , Kay-Tee Khaw , Christiane Maier , Walther Vogel , Manuel Luedeke , Kathleen Herkommer , Adam S Kibel , Cezary Cybulski , Dominika Wokolorczyk , Wojciech Kluzniak , Lisa Cannon-Albright , Hermann Brenner , Katarina Cuk , Kai-Uwe Saum , Jong Y Park , Thomas A Sellers , Chavdar Slavov , Radka Kaneva , Vanio Mitev , Jyotsna Batra , Judith A Clements , Amanda Spurdle , Manuel R Teixeira , Paula Paulo , Sofia Maia , Hardev Pandha , Agnieszka Michael , Andrzej Kierzek , David S Karow , Ian G Mills , Ole A Andreassen , Anders M Dale , The PRACTICAL Consortium*

Publication date (Electronic): January 10 2018

Journal: BMJ

Publisher: BMJ