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      Diazoxide in treatment of primary pulmonary hypertension.

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      British heart journal

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          Abstract

          Three patients with primary pulmonary hypertension and one man with suspected thromboembolic pulmonary hypertension were given up to 300 mg diazoxide by injection into the pulmonary artery. The three patients with primary pulmonary hypertension responded with a fall in total pulmonary resistance and a rise in cardiac output. The patient with suspected thromboembolic pulmonary hypertension did not respond. Haemodynamic and clinical improvement was maintained by oral diazoxide in two of the responders, and in one the prognosis appeared to be greatly improved.

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          Author and article information

          Journal
          Br Heart J
          British heart journal
          0007-0769
          0007-0769
          May 1978
          : 40
          : 5
          Article
          483448
          656227

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