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Evaluating the efficacy and safety of topical sirolimus 0.2% cream as adjuvant therapy with pulsed dye laser for the treatment of port wine stain: A randomized, double-blind, placebo-controlled trial.
Mahsa Fallahi
1
,
2 ,
Zahra Hallaji
1 ,
Soheil Tavakolpour
1
,
3 ,
Somayeh Niknam
4 ,
Ali Salehi Farid
1 ,
Ali Nili
1 ,
Amir Teimourpour
5 ,
Maryam Daneshpazhooh
1 ,
Javad Rahmati
6 ,
Shahriar Haddady Abianeh
6 ,
Hamidreza Mahmoudi
1
Aug 2021
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Abstract
Port Wine Stain (PWS) is a congenital capillary malformation. Although multiple treatments are required, the gold standard treatment for PWS is Pulsed Dye Laser (PDL). Given its anti-angiogenic effects, sirolimus can be considered as an adjuvant to PDL in PWS.