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      Treatment of Congestive Heart Failure: Pharmacological Principles

      Cardiology

      S. Karger AG

      CHF, principles of treatment, Congestive heart failure, CHF, pathophysiology, CHF, aetiology

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          Abstract

          Heart failure may result from different aetiologies: excessive afterload, depressed intrinsic contractility (generalized or regional), volume overload, and changes in diastolic properties. Compensatory mechanisms, such as the reflex increase in sympathetic tone, may initially be beneficial, but, in the long run, may become deleterious. Thus heart failure represents a very complex situation. Treatment should aim at: (a) removing the cause of heart failure; (b) improving contractile performance (by enhancement of the intrinsic contractile properties or by decreasing afterload); (c) moderating the major symptom-producing features (increased filling pressure), and decreasing peripheral demands for cardiac output.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          978-3-8055-4929-5
          978-3-318-01863-9
          0008-6312
          1421-9751
          1988
          1988
          11 November 2008
          : 75
          : Suppl 1
          : 61-66
          Affiliations
          Service of Cardiology, CHU, Liège, Belgium
          Article
          174446 Cardiology 1988;75:61–66
          10.1159/000174446
          3069217
          © 1988 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
          Categories
          Session II

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