Catheter Ablation of Left Ventricular Summit Ectopies in Left Ventricular Noncompaction

Abstract

Left ventricular noncompaction (LVNC) is a rare disorder and the true prevalence is largely unknown. Its clinical presentation is highly variable from being asymptomatic to the presence of heart failure, thromboembolic events, arrhythmias, and even risk of sudden cardiac death. A 37-year-old woman presented with frequent and symptomatic premature ventricular complexes (PVCs) and reduced left ventricular systolic function due to LVNC cardiomyopathy. The PVCs were refractory to medical therapy and the patient underwent successful ablation of the left ventricular summit PVCs. There was no recurrence of the PVCs at 6 months follow-up. This case report adds to the growing evidence of the efficacy and safety of performing radiofrequency ablation of ventricular arrhythmias (VAs) refractory to medical therapy in patients with LVNC. The different mechanisms of the VAs and therapeutic options are also reviewed.