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Abstract
There is little information in the English-language literature about the epidemiology
of salivary gland neoplasms in the eastern Chinese population. A large retrospective
study (6982 primary salivary tumors during 23 years) was carried out to investigate
the clinicopathological features (tumor location, patient sex and age) of these tumors
in this population. 3593 tumors were in males and 3389 in females. Pleomorphic adenoma
(69%) was the most common tumor and 20% were located in minor glands. 92% of Warthin's
tumors occurred in males. Malignant tumors were predominantly adenoid cystic carcinoma
(30%) and mucoepidermoid carcinoma (30%). Incidences of lymphoepithelial carcinomas
(5%) and polymorphous low-grade adenocarcinoma (1%) of malignant tumors were identified.
28% of tumors originated from minor glands. Most findings were similar to those in
the literature, with some variations. The salivary tumors slightly predominated in
males. Relatively higher incidences of minor gland tumors and specifically of pleomorphic
adenoma in minor glands were noted. Adenoid cystic carcinoma and mucoepidermoid carcinoma
constituted the most common malignancies. There was a high incidence of lymphoepithelial
carcinomas but a low incidence of polymorphous low-grade adenocarcinoma. The historical
significant male predominance of Warthin's tumor was confirmed.