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Treating viral hepatitis C: efficacy, side effects, and complications
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Abstract
The treatment of hepatitis C has dramatically improved over the past decade. Unlike
any other chronic viral infection, a significant proportion of patients with chronic
hepatitis C can be cured. However, the current standard therapy--pegylated interferon
alpha and ribavirin--has its limitations. Limited efficacy in patients with hepatitis
C virus (HCV) genotype 1 and the side effect profile will necessitate the development
of new therapeutic approaches. This review describes the efficacy and optimisation
of the current standard therapy of hepatitis C and its problems in special patient
populations. New treatment directions beyond interferon alpha based therapies are
on the horizon.