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      Reduction in saturated fat intake for cardiovascular disease

      Author(s): 1 , 2 , 1 , 1 , 1 , 1
      Editor(s): Cochrane Heart Group
      Publication date Created:
      Publication date (Electronic):
      Journal: Cochrane Database of Systematic Reviews
      Publisher: Wiley

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          Abstract

          Reducing saturated fat reduces serum cholesterol, but effects on other intermediate outcomes may be less clear. Additionally, it is unclear whether the energy from saturated fats eliminated from the diet are more helpfully replaced by polyunsaturated fats, monounsaturated fats, carbohydrate or protein.

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          Most cited references746

          • Record: found
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          Measuring inconsistency in meta-analyses.

          Julian P. T. Higgins, Simon Thompson, Jonathan Deeks … (2003)
          Article 0 comments Cited 9647 times – based on 0 reviews     Review now
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            Bias in meta-analysis detected by a simple, graphical test

            Jos I. M. Egger, G D Smith, M. Schneider … (1997)
            Article 0 comments Cited 6497 times – based on 0 reviews     Review now
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              Grading quality of evidence and strength of recommendations.

              David Atkins, Dana Best, Peter A Briss … (2004)
              Users of clinical practice guidelines and other recommendations need to know how much confidence they can place in the recommendations. Systematic and explicit methods of making judgments can reduce errors and improve communication. We have developed a system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts. In this article we present a summary of our approach from the perspective of a guideline user. Judgments about the strength of a recommendation require consideration of the balance between benefits and harms, the quality of the evidence, translation of the evidence into specific circumstances, and the certainty of the baseline risk. It is also important to consider costs (resource utilisation) before making a recommendation. Inconsistencies among systems for grading the quality of evidence and the strength of recommendations reduce their potential to facilitate critical appraisal and improve communication of these judgments. Our system for guiding these complex judgments balances the need for simplicity with the need for full and transparent consideration of all important issues.
              Article 0 comments Cited 1101 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (publisher-id): 146518
                Title: Cochrane Database of Systematic Reviews
                Publisher: Wiley
                ISSN (Electronic): 14651858
                Publication date Created: August 2020
                Publication date (Electronic): August 21 2020
                Volume: 2020
                Issue: 8
                Affiliations
                [1 ]Norwich Medical School; University of East Anglia; Norwich UK
                [2 ]Institute of Health Informatics Research; University College London; London UK
                Article
                DOI: 10.1002/14651858.CD011737.pub3
                PMC ID: 8092457
                PubMed ID: 32827219
                SO-VID: 2efdb085-2091-4650-958d-602bfb21bbb7
                Copyright © © 2020
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