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      Posttraumatic stress disorder symptoms among trauma-exposed adolescents from low- and middle-income countries

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          Abstract

          Background

          Exposure to traumatic events in childhood is associated with the development and maintenance of various psychiatric disorders, but most frequently with posttraumatic stress disorder (PTSD). The aim of this study was to evaluate the types of traumatic events experienced and the presence and predictors of PTSD symptoms among adolescents from the general population from ten low- and middle-income countries (LMICs).

          Methods

          Data were simultaneously collected from 3370 trauma-exposed adolescents (mean age = 15.41 [SD = 1.65] years, range 12–18; 1465 (43.5%) males and 1905 (56.5%) females) in Brazil, Bulgaria, Croatia, Indonesia, Montenegro, Nigeria, the Palestinian Territories, the Philippines, Romania, and Serbia, with Portugal, a high-income country, as a reference point. The UCLA PTSD Reaction Index for the DSM-5 (PTSD-RI-5) was used for the assessment of traumatic events and PTSD symptoms.

          Results

          The most frequently reported traumatic events were death of a close person (69.7%), witnessing violence other than domestic (40.5%), being in a natural disaster (34.4%) and witnessing violent death or serious injury of a close person (33.9%). In total, 28.5% adolescents endorsed two to three DSM-5 PTSD criteria symptoms. The rates of adolescents with symptoms from all four DSM-5 criteria for PTSD were 6.2–8.1% in Indonesia, Serbia, Bulgaria, and Montenegro, and 9.2–10.5% in Philippines, Croatia and Brazil. From Portugal, 10.7% adolescents fall into this category, while 13.2% and 15.3% for the Palestinian Territories and Nigeria, respectively. A logistic regression model showed that younger age, experiencing war, being forced to have sex, and greater severity of symptoms (persistent avoidance, negative alterations in cognitions and mood, and alterations in arousal and reactivity) were significant predictors of fulfilling full PTSD criteria.

          Conclusions

          Nearly every third adolescent living in LMICs might have some PTSD symptoms after experiencing a traumatic event, while nearly one in ten might have sufficient symptoms for full DSM-5 PTSD diagnosis. The findings can inform the generation of PTSD burden estimates, allocation of health resources, and designing and implementing psychosocial interventions for PTSD in LMICs.

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          Most cited references46

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          The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium.

          Considerable research has documented that exposure to traumatic events has negative effects on physical and mental health. Much less research has examined the predictors of traumatic event exposure. Increased understanding of risk factors for exposure to traumatic events could be of considerable value in targeting preventive interventions and anticipating service needs.
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            Annual Research Review: Enduring neurobiological effects of childhood abuse and neglect.

            Childhood maltreatment is the most important preventable cause of psychopathology accounting for about 45% of the population attributable risk for childhood onset psychiatric disorders. A key breakthrough has been the discovery that maltreatment alters trajectories of brain development.
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              Considering PTSD for DSM-5.

              This is a review of the relevant empirical literature concerning the DSM-IV-TR diagnostic criteria for PTSD. Most of this work has focused on Criteria A1 and A2, the two components of the A (Stressor) Criterion. With regard to A1, the review considers: (a) whether A1 is etiologically or temporally related to the PTSD symptoms; (b) whether it is possible to distinguish "traumatic" from "non-traumatic" stressors; and (c) whether A1 should be eliminated from DSM-5. Empirical literature regarding the utility of the A2 criterion indicates that there is little support for keeping the A2 criterion in DSM-5. The B (reexperiencing), C (avoidance/numbing) and D (hyperarousal) criteria are also reviewed. Confirmatory factor analyses suggest that the latent structure of PTSD appears to consist of four distinct symptom clusters rather than the three-cluster structure found in DSM-IV. It has also been shown that in addition to the fear-based symptoms emphasized in DSM-IV, traumatic exposure is also followed by dysphoric, anhedonic symptoms, aggressive/externalizing symptoms, guilt/shame symptoms, dissociative symptoms, and negative appraisals about oneself and the world. A new set of diagnostic criteria is proposed for DSM-5 that: (a) attempts to sharpen the A1 criterion; (b) eliminates the A2 criterion; (c) proposes four rather than three symptom clusters; and (d) expands the scope of the B-E criteria beyond a fear-based context. The final sections of this review consider: (a) partial/subsyndromal PTSD; (b) disorders of extreme stress not otherwise specified (DESNOS)/complex PTSD; (c) cross- cultural factors; (d) developmental factors; and (e) subtypes of PTSD. © 2010 Wiley-Liss, Inc.
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                Author and article information

                Contributors
                rajna.knez@gu.se
                Journal
                Child Adolesc Psychiatry Ment Health
                Child Adolesc Psychiatry Ment Health
                Child and Adolescent Psychiatry and Mental Health
                BioMed Central (London )
                1753-2000
                5 June 2021
                5 June 2021
                2021
                : 15
                : 26
                Affiliations
                [1 ]Clinic for Neurology and Psychiatry for Children and Youth, Belgrade, Serbia
                [2 ]GRID grid.9918.9, ISNI 0000 0004 1936 8411, School of Psychology, , Leicester University, ; Leicester, UK
                [3 ]GRID grid.411276.7, ISNI 0000 0001 0725 8811, Department of Behavioural Medicine, , Lagos State University College of Medicine Ikeja, ; Lagos, Nigeria
                [4 ]GRID grid.410917.a, ISNI 0000 0001 1958 0680, Lusíada University, ; Porto, Portugal
                [5 ]CIPD, Porto, Portugal
                [6 ]GRID grid.412680.9, ISNI 0000 0001 1015 399X, Medical Faculty Osijek, , University Health Center Osijek, ; Osijek, Croatia
                [7 ]GRID grid.38603.3e, ISNI 0000 0004 0644 1675, Child and Adolescent Psychiatry, School of Medicine, , University of Split, ; Split, Croatia
                [8 ]GRID grid.22939.33, ISNI 0000 0001 2236 1630, Department of Psychology, Faculty of Humanities and Social Sciences, ; Rijeka, Croatia
                [9 ]Faculty of Psychology, State Islamic University Syarif Hidayatullah, Jakarta, Indonesia
                [10 ]Dr Soeharto Heerdjan Mental Hospital Jakarta, Jakarta, Indonesia
                [11 ]GRID grid.22248.3e, ISNI 0000 0001 0504 4027, Department of Child and Adolescent Psychiatry, , University of Medicine and Pharmacy “Victor Babes”, ; Timisoara, Romania
                [12 ]School of Public Health, Gaza Branch, Al Quds University, Jerusalem, Palestinian Territories Israel
                [13 ]Department of Psychology, St. Dominic College of Asia, City of Bacoor, Bacoor, Philippines
                [14 ]GRID grid.460112.0, Department of Child and Adolescent Psychiatry, , University Hospital St. Marina, ; Varna, Bulgaria
                [15 ]Mental Health Center, Pljevlja, Montenegro
                [16 ]GRID grid.412303.7, ISNI 0000 0001 1954 6327, Universidade Estacio de Sá in Rio de Janeiro, ; Rio de Janeiro, Brazil
                [17 ]GRID grid.8536.8, ISNI 0000 0001 2294 473X, Federal University of Rio de Janeiro, ; Rio de Janeiro, Brazil
                [18 ]GRID grid.412710.1, ISNI 0000 0004 0587 2414, Psychiatric Clinic, Clinical Center Kragujevac, ; Kragujevac, Serbia
                [19 ]GRID grid.410917.a, ISNI 0000 0001 1958 0680, Lusíada University, ; Porto, Portugal
                [20 ]GRID grid.416029.8, ISNI 0000 0004 0624 0275, Department of Pediatrics, , Skaraborgs Hospital Skövde, ; Skövde, Sweden
                [21 ]GRID grid.8761.8, ISNI 0000 0000 9919 9582, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, , University of Gothenburg, ; Gothenburg, Sweden
                Author information
                http://orcid.org/0000-0003-1278-4554
                Article
                378
                10.1186/s13034-021-00378-2
                8180049
                34090487
                31132624-bf3e-43ec-87ee-ee22707b813a
                © The Author(s) 2021

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 22 September 2019
                : 27 May 2021
                Funding
                Funded by: University of Gothenburg
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2021

                Clinical Psychology & Psychiatry
                traumatic events,prevalence,culture,ptsd-ri-5,ucla ptsd index
                Clinical Psychology & Psychiatry
                traumatic events, prevalence, culture, ptsd-ri-5, ucla ptsd index

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