We discuss the QDN (quantized detector network) approach to the formulation and interpretation of quantum mechanics. This approach gives us a system-free approach to quantum physics. By this, we mean having a proper emphasis on those aspects of physics which are observable and an avoidance of metaphysical concepts, which by definition are incapable of verification and should play no role in science on that account. By focusing on only what experimentalists deal with, i.e., quantum information, we avoid the ambiguities and confusion generated by the undue objectification of what are complex quantum processes.