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      Fixed-dose combination of AR-13324 and latanoprost: a double-masked, 28-day, randomised, controlled study in patients with open-angle glaucoma or ocular hypertension.

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          Abstract

          To evaluate the ocular hypotensive efficacy of fixed-dose combinations of the Rho kinase inhibitor and norepinephrine transport inhibitor AR-13324 (0.01% and 0.02%) and latanoprost (PG324 Ophthalmic Solution) relative to the active components AR-13324 0.02% and latanoprost 0.005%, used bilaterally at night.

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          Author and article information

          Journal
          Br J Ophthalmol
          The British journal of ophthalmology
          BMJ
          1468-2079
          0007-1161
          Mar 2016
          : 100
          : 3
          Affiliations
          [1 ] Sacramento Eye Consultants, Sacramento, California, USA.
          [2 ] Aerie Pharmaceuticals Inc., Bridgewater, Bridgewater, New Jersey, USA/Research Triangle Park, North Carolina, USA SDC Inc., Tempe, Arizona, USA.
          [3 ] SDC Inc., Tempe, Arizona, USA.
          [4 ] PharmaLogic Development Inc., San Rafael, California, USA.
          Article
          bjophthalmol-2015-306778
          10.1136/bjophthalmol-2015-306778
          26209587
          34e35330-81c4-4212-bfb2-f25168b95c5c
          History

          Glaucoma,Intraocular pressure
          Glaucoma, Intraocular pressure

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