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      Correction: Lung density change after SABR: A comparative study between tri-Co-60 magnetic resonance-guided system and linear accelerator

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          The following information is missing from the Funding section: This study was also supported by the National Research Foundation of Korea (NRF), which is funded by the Korea government (MEST, Grant No. 2014M2A2A7055063).

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          Lung density change after SABR: A comparative study between tri-Co-60 magnetic resonance-guided system and linear accelerator

          Eunji Kim, Hong-Gyun Wu, Jong Min Park … (2018)
          Radiation-induced lung damage is an important treatment-related toxicity after lung stereotactic ablative radiotherapy (SABR). After implementing a tri-60Co magnetic-resonance image guided system, ViewRayTM, we compared the associated early radiological lung density changes to those associated with a linear accelerator (LINAC). Eight patients treated with the tri-60Co system were matched 1:1 with patients treated with LINAC. Prescription doses were 52 Gy or 60 Gy in four fractions, and lung dose-volumetric parameters were calculated from each planning system. The first two follow-up computed tomography (CT) were co-registered with the planning CT through deformable registration software, and lung density was measured by isodose levels. Tumor size was matched between the two groups, but the planning target volume of LINAC was larger than that of the tri-60Co system (p = 0.036). With regard to clinically relevant dose-volumetric parameters in the lungs, the ipsilateral lung mean dose, V 10Gy and V 20Gy were significantly poorer in tri-60Co plans compared to LINAC plans (p = 0.012, 0.036, and 0.017, respectively). Increased lung density was not observed in the first follow-up scan compared to the planning scan. A significant change of lung density was shown in the second follow-up scan and there was no meaningful difference between the tri-60Co system and LINAC for all dose regions. In addition, no patient developed clinical radiation pneumonitis until the second follow-up scan. Therefore, there was no significant difference in the early radiological lung damage between the tri-60Co system and LINAC for lung SABR despite of the inferior plan quality of the tri-60Co system compared to that of LINAC. Further studies with a longer follow-up period are needed to confirm our findings.
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            Journal
            Journal ID (nlm-ta): PLoS One
            Journal ID (iso-abbrev): PLoS ONE
            Journal ID (publisher-id): plos
            Journal ID (pmc): plosone
            Title: PLoS ONE
            Publisher: Public Library of Science (San Francisco, CA USA )
            ISSN (Electronic): 1932-6203
            Publication date (Electronic): 17 May 2018
            Publication date Collection: 2018
            Publication date PMC-release: 17 May 2018
            Volume: 13
            Issue: 5
            Electronic Location Identifier: e0197799
            Article
            Publisher ID: PONE-D-18-14131
            DOI: 10.1371/journal.pone.0197799
            PMC ID: 5957376
            PubMed ID: 29771972
            SO-VID: 3b172636-8abb-463f-876c-884302c88a68
            Copyright © © 2018 Kim et al
            License:

            This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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            Lung density change after SABR: A comparative study between tri-Co-60 magnetic resonance-guided system and linear accelerator
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