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      Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment

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          Abstract

          The appropriate sequencing of agents with strong immune system effects has become increasingly important. Transitions require careful balance between safety and protection against relapse. The cases presented herein highlight that rebound events after ceasing fingolimod treatment may happen even with short washout periods (4 weeks) and may perpetuate despite steroid treatment or the immediate use of fast-acting immune therapies, such as rituximab.

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          Author and article information

          Journal
          JAMA Neurology
          JAMA Neurol
          American Medical Association (AMA)
          2168-6149
          July 01 2016
          July 01 2016
          : 73
          : 7
          : 790
          Affiliations
          [1 ]Department of Neurology, University of California, San Francisco
          Article
          10.1001/jamaneurol.2016.0826
          27135594
          3ca342b1-eca6-414e-bc1b-e3702a0003ce
          © 2016
          History

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