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      Growth Hormone Treatment Does Not Alter Lower Limb Asymmetry in Children with Russell-Silver Syndrome

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          Background: Growth hormone (GH) treatment has been proven to have a beneficial effect on growth in children with Russell-Silver syndrome (RSS). Methods: We describe 7 prepubertal children with RSS and lower limb asymmetry treated with GH for 3 years. Results: There was a significant increase in height without any significant change in the asymmetry. Conclusions: We conclude that the rapid growth acceleration to GH treatment does not alter the lower limb asymmetry in children with RSS.

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          Growth Hormone Treatment in Growth Hormone-Sufficient and -Insufficient Children with Intrauterine Growth Retardation/Russell-Silver Syndrome


            Author and article information

            Horm Res Paediatr
            Hormone Research in Paediatrics
            S. Karger AG
            15 February 2002
            : 56
            : 3-4
            : 114-116
            Department of Paediatric Endocrinology, Great Ormond Street Hospital for Children and Middlesex Hospital (UCLH), London, UK
            48102 Horm Res 2001;56:114–116
            © 2002 S. Karger AG, Basel

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            Figures: 1, References: 12, Pages: 3
            Original Paper


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