The extended Infant Feeding, Activity and Nutrition Trial (InFANT Extend) Program: a cluster-randomized controlled trial of an early intervention to prevent childhood obesity

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Abstract

Background

Understanding how we can prevent childhood obesity in scalable and sustainable ways is imperative. Early RCT interventions focused on the first two years of life have shown promise however, differences in Body Mass Index between intervention and control groups diminish once the interventions cease. Innovative and cost-effective strategies seeking to continue to support parents to engender appropriate energy balance behaviours in young children need to be explored.

Methods/Design

The Infant Feeding Activity and Nutrition Trial (InFANT) Extend Program builds on the early outcomes of the Melbourne InFANT Program. This cluster randomized controlled trial will test the efficacy of an extended (33 versus 15 month) and enhanced (use of web-based materials, and Facebook® engagement), version of the original Melbourne InFANT Program intervention in a new cohort. Outcomes at 36 months of age will be compared against the control group.

Discussion

This trial will provide important information regarding capacity and opportunities to maximize early childhood intervention effectiveness over the first three years of life. This study continues to build the evidence base regarding the design of cost-effective, scalable interventions to promote protective energy balance behaviors in early childhood, and in turn, promote improved child weight and health across the life course.

Trial registration

ACTRN12611000386932. Registered 13 April 2011.

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Most cited references 37

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Consistent dietary patterns identified from childhood to adulthood: the cardiovascular risk in Young Finns Study.

V Mikkilä, L Räsänen, O. Raitakari … (2005)

Dietary patterns are useful in nutritional epidemiology, providing a comprehensive alternative to the traditional approach based on single nutrients. The Cardiovascular Risk in Young Finns Study is a prospective cohort study with a 21-year follow-up. At baseline, detailed quantitative information on subjects' food consumption was obtained using a 48 h dietary recall method (n 1768, aged 3-18 years). The interviews were repeated after 6 and 21 years (n 1200 and n 1037, respectively). We conducted a principal component analysis to identify major dietary patterns at each study point. A set of two similar patterns was recognised throughout the study. Pattern 1 was positively correlated with consumption of traditional Finnish foods, such as rye, potatoes, milk, butter, sausages and coffee, and negatively correlated with fruit, berries and dairy products other than milk. Pattern 1 type of diet was more common among male subjects, smokers and those living in rural areas. Pattern 2, predominant among female subjects, non-smokers and in urban areas, was characterised by more health-conscious food choices such as vegetables, legumes and nuts, tea, rye, cheese and other dairy products, and also by consumption of alcoholic beverages. Tracking of the pattern scores was observed, particularly among subjects who were adolescents at baseline. Of those originally belonging to the uppermost quintile of pattern 1 and 2 scores, 41 and 38 % respectively, persisted in the same quintile 21 years later. Our results suggest that food behaviour and concrete food choices are established already in childhood or adolescence and may significantly track into adulthood.

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How can we increase translation of research into practice? Types of evidence needed.

Russell E. Glasgow, Karen Emmons (2007)

This review summarizes key factors that have interfered with translation of research to practice and what public health researchers can do to hasten such transfer, focusing on characteristics of interventions, target settings, and research designs. The need to address context and to utilize research, review, and reporting practices that address external validity issues-such as designs that focus on replication, and practical clinical and behavioral trials-are emphasized. Although there has been increased emphasis on social-ecological interventions that go beyond the individual level, interventions often address each component as if it were an independent intervention. Greater attention is needed to connectedness across program levels and components. Finally, examples are provided of evaluation models and current programs that can help accelerate translation of research to practice and policy.

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The Anti Cancer Council of Victoria FFQ: relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation.

Allison M. Hodge, Amanda J Patterson, Wendy Brown … (2000)

To assess the validity of the Anti Cancer Council of Victoria food frequency questionnaire (ACCVFFQ) relative to seven-day weighed food records (WFRs) in 63 women of child-bearing age. 63 women completed WFRs to assess iron intake as part of a study on iron deficiency. These women also completed the ACCVFFQ. Nutrient intakes were computed independently for the WFRs and FFQs. Intakes were compared as group means, by correlation and by quintile classification, adjusting for day-to-day variation in intakes, and for energy intake. Individual differences in results were also examined. The strongest associations between WFR and FFQ results were energy-adjusted, log-transformed and adjusted for day-to-day variability in intake. Correlation coefficients ranged from 0.28 for vitamin A to 0.78 for carbohydrate. Mean intakes from the WFRs and FFQs were within +/- 20% for 21 of 27 nutrients. Poor agreement between FFQs and WFRs for retinol intake was due to the inclusion of liver in two WFRs, an item which is not included in the FFQ. The ACCVFFQ performs as well as other FFQs for which validation data are available. The relatively poor measurement of retinol is consistent with other data, and with the limited number of foods in which this nutrient is abundant. The availability of an optically scannable valid instrument for assessing dietary intake will facilitate epidemiological studies of diet and disease, an area of current research priority.

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Author and article information

Contributors

Karen J. Campbell: karen.campbell@deakin.edu.au

Kylie D. Hesketh: kylie.hesketh@deakin.edu.au

Sarah A. McNaughton: sarah.mcnaughton@deakin.edu.au

Kylie Ball: kylie.ball@deakin.edu.au

Zoë McCallum: zoe.mccallum@rch.org.au

John Lynch: john.lynch@adelaide.edu.au

David A. Crawford: david.crawford@deakin.edu.au

Journal

Journal ID (nlm-ta): BMC Public Health

Journal ID (iso-abbrev): BMC Public Health

Title: BMC Public Health

Publisher: BioMed Central (London )

ISSN (Electronic): 1471-2458

Publication date (Electronic): 18 February 2016

Publication date PMC-release: 18 February 2016

Publication date Collection: 2016

Volume: 16

Electronic Location Identifier: 166

Affiliations

[ ]Deakin University, Centre for Physical Activity and Nutrition Research, School of Exercise and Nutrition Sciences, Faculty of Health, Victoria, Australia

[ ]Department of Pediatrics, University of Melbourne, Victoria, Australia

[ ]School of Public Health, University of Adelaide, South Australia, Australia

Article

Publisher ID: 2836

DOI: 10.1186/s12889-016-2836-0

PMC ID: 4758178

PubMed ID: 26888759

SO-VID: 3e234ffe-038f-4cb3-b151-8776d7722b10

License:

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

History

Date received : 7 January 2016

Date accepted : 4 February 2016

Funding

Funded by: FundRef http://dx.doi.org/10.13039/501100000321, World Cancer Research Fund;

Award ID: 2010/244

Award Recipient : Karen J. Campbell

Custom metadata

ScienceOpen disciplines: Public health

Keywords: randomized controlled trial,infant,early-childhood,obesity,prevention,intervention,scalability,feeding,physical-activity,screen-time

Data availability:

ScienceOpen disciplines: Public health

Keywords: randomized controlled trial, infant, early-childhood, obesity, prevention, intervention, scalability, feeding, physical-activity, screen-time

The extended Infant Feeding, Activity and Nutrition Trial (InFANT Extend) Program: a cluster-randomized controlled trial of an early intervention to prevent childhood obesity

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Abstract

Background

Methods/Design

Discussion

Trial registration

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Point-of-Care Testing for Infectious Diseases Super Collection

Most cited references 37

Consistent dietary patterns identified from childhood to adulthood: the cardiovascular risk in Young Finns Study.

How can we increase translation of research into practice? Types of evidence needed.

The Anti Cancer Council of Victoria FFQ: relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation.

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