We study spin transport in a Hubbard chain with strong, random, on--site potential and with spin--dependent hopping integrals, \(t_{\sigma}\). For the the SU(2) symmetric case, \(t_{\uparrow} =t_{\downarrow}\), such model exhibits only partial many-body localization with localized charge and (delocalized) subdiffusive spin excitations. Here, we demonstrate that breaking the SU(2) symmetry by even weak spin--asymmetry, \(t_{\uparrow} \ne t_{\downarrow}\), localizes spins and restores full many-body localization. To this end we derive an effective spin model, where the spin subdiffusion is shown to be destroyed by arbitrarily weak \(t_{\uparrow} \ne t_{\downarrow}\). Instability of the spin subdiffusion originates from an interplay between random effective fields and singularly distributed random exchange interactions.