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      Imaging features of the aging spine

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          Abstract

          Among many degenerative abnormalities commonly found in spine imaging, not all are associated with the patient’s symptoms. We aimed to assess features of the standard, asymptomatic aging process of the spine. In this narrative review, we emphasize studies that describe imaging features of the spine in asymptomatic populations of different age groups. Degeneration of the intervertebral discs, bulging, and facet joint arthropathy have been documented in almost 90% of asymptomatic patients over 60 years of age. After the age of 40 years, nearly all patients have anterior and lateral vertebral osteophytes, whereas posterior osteophytes are found in a minority of them. There is a gradual increase in vertebral bone marrow fat composition with age with the acceleration of this process in women after menopause. The prevalence of these findings is common in asymptomatic populations and varies depending on the patient’s age. It is essential to differentiate likely natural and age-related findings from pathological abnormalities to make an accurate diagnosis.

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          Most cited references60

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          Magnetic resonance classification of lumbar intervertebral disc degeneration.

          A reliability study was conducted. To develop a classification system for lumbar disc degeneration based on routine magnetic resonance imaging, to investigate the applicability of a simple algorithm, and to assess the reliability of this classification system. A standardized nomenclature in the assessment of disc abnormalities is a prerequisite for a comparison of data from different investigations. The reliability of the assessment has a crucial influence on the validity of the data. Grading systems of disc degeneration based on state of the art magnetic resonance imaging and corresponding reproducibility studies currently are sparse. A grading system for lumbar disc degeneration was developed on the basis of the literature. An algorithm to assess the grading was developed and optimized by reviewing lumbar magnetic resonance examinations. The reliability of the algorithm in depicting intervertebral disc alterations was tested on the magnetic resonance images of 300 lumbar intervertebral discs in 60 patients (33 men and 27 women) with a mean age of 40 years (range, 10-83 years). All scans were analyzed independently by three observers. Intra- and interobserver reliabilities were assessed by calculating kappa statistics. There were 14 Grade I, 82 Grade II, 72 Grade III, 68 Grade IV, and 64 Grade V discs. The kappa coefficients for intra- and interobserver agreement were substantial to excellent: intraobserver (kappa range, 0.84-0.90) and interobserver (kappa range, 0.69-0.81). Complete agreement was obtained, on the average, in 83.8% of all the discs. A difference of one grade occurred in 15.9% and a difference of two or more grades in 1.3% of all the cases. Disc degeneration can be graded reliably on routine T2-weighted magnetic resonance images using the grading system and algorithm presented in this investigation.
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            Systematic literature review of imaging features of spinal degeneration in asymptomatic populations.

            Degenerative changes are commonly found in spine imaging but often occur in pain-free individuals as well as those with back pain. We sought to estimate the prevalence, by age, of common degenerative spine conditions by performing a systematic review studying the prevalence of spine degeneration on imaging in asymptomatic individuals.
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              Human intervertebral disc: structure and function.

              This review begins with a brief introduction in which the development, blood supply and innervation of the intervertebral disc is considered, particularly as these may influence the following sections on structure and function. The three regions within the disc--that is, the nucleus pulposus, annulus fibrosus, and cartilage end plates--are considered in some detail. There appears to be no distinct border between the central nucleus pulposus and the outer annulus fibrosus, the main difference being in their fibrous structure. The fluid space is important in the nutrition of the disc, showing plastic deformation and recovery characteristics. The structural elements, both macroscopically and microscopically, together with the biochemical elements, are intimately related to function. The intervertebral disc should not be though of as a homogeneous and static structure; it has a heterogeneous composition and responds dynamically to applied loads. Neither should it be considered as an isolated structure because it interacts with the vertebral bodies, together constituting the vertebral unit. Furthermore, changes within the disc can, and do, have dramatic effects on vertebral column kinematics. The intervertebral disc is not inactive; it is capable of self-maintenance; in injury it can repair itself and has considerable regenerative properties.
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                Author and article information

                Journal
                Pol J Radiol
                Pol J Radiol
                PJR
                Polish Journal of Radiology
                Termedia Publishing House
                1733-134X
                1899-0967
                28 June 2021
                2021
                : 86
                : e380-e386
                Affiliations
                [1 ]Department of Diagnostic Imaging, Gruca Teaching Hospital, Medical Center of Postgraduate Education, Otwock, Poland
                [2 ]Department of Diagnostic Radiology, Central Clinical Hospital of the Ministry of the Interior in Warsaw, Poland
                Author notes
                Correspondence address: Krzysztof Wocial, Department of Diagnostic Imaging, Gruca Teaching Hospital, Medical Center of Postgraduate Education, Otwock, Poland, e-mail: krzysztofw.wocial@ 123456gmail.com
                [A]

                Study design

                [B]

                Data collection

                [C]

                Statistical analysis

                [D]

                Data interpretation

                [E]

                Manuscript preparation

                [F]

                Literature search

                [G]

                Funds collection

                Article
                44683
                10.5114/pjr.2021.107728
                8297484
                34322188
                3f0dd5f9-e0c4-4473-baca-79bf1c3f847a
                Copyright © Polish Medical Society of Radiology 2021

                This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0). License ( https://creativecommons.org/licenses/by-nc-nd/4.0/)

                History
                : 10 August 2020
                : 04 September 2020
                Categories
                Review Paper

                Radiology & Imaging
                aging,spine,mri,asymptomatic
                Radiology & Imaging
                aging, spine, mri, asymptomatic

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