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      Attitudes towards COVID-19 vaccination, vaccine hesitancy and intention to take the vaccine

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          Abstract

          Background:

          The pandemic is at a paradoxical stage, with vaccine roll out initiated but a significantly elevated level of infection and death. Hope for recovery lies in high equitable vaccine uptake.

          Objective:

          The study aimed to: i) explore attitudes and factors influencing attitudes, towards the COVID-19 vaccine amongst people living in Malta, ii) identify the reasons as to why individuals are unsure or unwilling to take the vaccine.

          Methods:

          Two consecutive, short, anonymous online surveys using social media platforms were used to gather data from adult individuals. The first study was open to residents in Malta, while the second study invited international participation. Study 1 consisted of 17 questions inspired by the Theories of Planned Behaviour and Reasoned Action. Study 2 asked participates whether they were willing, unwilling or unsure of taking the vaccine and their reasons for being unsure or unwilling.

          Results:

          A total of 2,529 individuals participated in Study 1 and 834 in Study 2. In both studies respondents were predominantly female having a tertiary education. Over 50% declared that they were willing to take the vaccine, with males being more willing (t=5.83, df=1164.2, p<0.00005). Opinions of significant others- family and friends (r=0.22, p<0.005) and health professionals (r=0.74, p<0.005) were associated with willingness to take the vaccine. Vaccine hesitancy was present in the study population with 32.6% being unsure and 15.6% declaring that they were not willing to take the vaccine. Females were more likely to be unsure (Chi-squared=14.63, df=4, p=0.006). Lack of vaccine safety was the main reason cited for unwillingness to take the vaccine. Predictors for willingness to take the vaccine were: i) The belief that the COVID-19 vaccine will protect the health of the people who take it; ii) Valuing the advice of health professionals regarding the effectiveness of COVID-19 vaccine; iii) Having taken the influenza vaccine last year and; iv) Encouraging their elderly parents to take the vaccine.

          Conclusions:

          COVID-19 vaccination information campaigns should promote group strategies, focusing on emphasising the safety of the vaccine and offer reassurance, especially to women.

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          Most cited references40

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          Vaccine hesitancy: Definition, scope and determinants.

          The SAGE Working Group on Vaccine Hesitancy concluded that vaccine hesitancy refers to delay in acceptance or refusal of vaccination despite availability of vaccination services. Vaccine hesitancy is complex and context specific, varying across time, place and vaccines. It is influenced by factors such as complacency, convenience and confidence. The Working Group retained the term 'vaccine' rather than 'vaccination' hesitancy, although the latter more correctly implies the broader range of immunization concerns, as vaccine hesitancy is the more commonly used term. While high levels of hesitancy lead to low vaccine demand, low levels of hesitancy do not necessarily mean high vaccine demand. The Vaccine Hesitancy Determinants Matrix displays the factors influencing the behavioral decision to accept, delay or reject some or all vaccines under three categories: contextual, individual and group, and vaccine/vaccination-specific influences.
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            A global survey of potential acceptance of a COVID-19 vaccine

            Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. In June 2020, we surveyed 13,426 people in 19 countries to determine potential acceptance rates and factors influencing acceptance of a COVID-19 vaccine. Of these, 71.5% of participants reported that they would be very or somewhat likely to take a COVID-19 vaccine, and 61.4% reported that they would accept their employer’s recommendation to do so. Differences in acceptance rates ranged from almost 90% (in China) to less than 55% (in Russia). Respondents reporting higher levels of trust in information from government sources were more likely to accept a vaccine and take their employer’s advice to do so.
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              Attitudes Toward a Potential SARS-CoV-2 Vaccine: A Survey of U.S. Adults

              Once a vaccine for coronavirus disease 2019 becomes available, it will be important to maximize vaccine uptake and coverage. This national survey explores factors associated with vaccine hesitancy. The results suggest that multipronged efforts will be needed to increase acceptance of a coronavirus disease 2019 vaccine.
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                Author and article information

                Contributors
                Journal
                Pharm Pract (Granada)
                Pharm Pract (Granada)
                Pharmacy Practice
                Centro de Investigaciones y Publicaciones Farmaceuticas
                1885-642X
                1886-3655
                Jan-Mar 2021
                22 March 2021
                : 19
                : 1
                : 2317
                Affiliations
                BPharm (Hons.), PhD. Associate Professor, Department of Clinical Pharmacology and Therapeutics. WHO Collaborating Centre for Health Professionals Education and Research, Faculty of Medicine and Surgery, University of Malta . Msida (Malta). maria.cordina@ 123456um.edu.mt
                BA (Hons),MSc, PhD, CPsychol. Professor. Department of Psychology, Faculty of Social Well Being, University of Malta . Msida (Malta). mary-anne.lauri@ 123456um.edu.mt
                BSc.,MSc, PhD. Professor. Department of Mathematics, Faculty of Science, University of Malta . Msida (Malta). josef.lauri@ 123456um.edu.mt
                Author notes

                Conceptualization. MC, MAL, JL. Data curation. JL. formal analysis. JL. Investigation. MC, MAL, JL. Methodology. MC, MAL, JL. Project administration. MC. Validation. JL. Visualization. MC, MAL, JL. Writing – original draft. MC, JL. Writing – review & editing. MC, MAL, JL.

                Author information
                https://orcid.org/0000-0002-7498-2874
                https://orcid.org/0000-0001-5219-8010
                https://orcid.org/0000-0001-6338-963X
                Article
                pharmpract-19-2317
                10.18549/PharmPract.2021.1.2317
                8005329
                33828623
                3f819f05-d758-4ac5-a1c7-a16d32c553f7
                Copyright: © Pharmacy Practice and the authors

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY-NC-ND 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 05 February 2021
                : 21 March 2021
                Categories
                Original Research

                covid-19 vaccines,immunization programs,vaccination,vaccination refusal,attitude,health knowledge,attitudes,practice,covid-19,sars-cov-2,pandemics,health belief model,cross-sectional studies,malta

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