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      The comparison of Filgrastim (Neupogen®), biosimilar filgrastim (Leucostim®) and Lenograstim (Granocyte®) as a first line peripheral blood stem cell mobilization strategy in autologous hematopoieitic stem cell transplantation: a single center experience from Turkey.

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          Abstract

          Patients affected by hematological malignancies can often benefit from high dose chemotherapy followed by peripheral blood stem cells (PBSCs) transplantation. Different strategies have been used to mobilize an adequate number of PBSC, including granulocyte colony-stimulating factor (G-CSF) alone or chemotherapy plus G-CSF. In this study, we aimed to compare the efficacy profile of different G-CSF agents including filgrastim (Neupogen®), biosimilar filgrastim (Leucostim®) and Lenograstim (Granocyte®) on CD34(+) mobilization in patients who underwent autologous hematopoietic stem cell transplantation (autoHSCT).

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          Author and article information

          Journal
          Transfus. Apher. Sci.
          Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
          Elsevier BV
          1473-0502
          1473-0502
          Jun 2013
          : 48
          : 3
          Affiliations
          [1 ] Dedeman Stem Cell Transplantation Hospital, Department of Hematology, Faculty of Medicine, Erciyes University, Kayseri, Turkey. drssivgin@gmail.com
          Article
          S1473-0502(13)00092-X
          10.1016/j.transci.2013.04.007
          23611684
          41b00604-187f-4f86-a867-4a23b7a38f4c
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