The present study provides a species list of freshwater mussels from Catalão, the meeting of the Solimões and Negro rivers, in state of Amazonas, northern Brazil. Expeditions to collect molluscs were carried out between 2004 and 2006, during high and low water seasons. Three hundred and thirty-one bivalve shells, 25 valves, and 57 live specimens of four families and 10 species were identified. A single exotic species, Corbicula fluminea, represented over half the collected shells. All bivalve shells were photographed and registered at the mollusc collection of the Instituto Nacional de Pesquisas da Amazônia (INPA), Manaus.