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      An Efficient Automatic Mass Classification Method In Digitized Mammograms Using Artificial Neural Network

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          Abstract

          In this paper we present an efficient computer aided mass classification method in digitized mammograms using Artificial Neural Network (ANN), which performs benign-malignant classification on region of interest (ROI) that contains mass. One of the major mammographic characteristics for mass classification is texture. ANN exploits this important factor to classify the mass into benign or malignant. The statistical textural features used in characterizing the masses are mean, standard deviation, entropy, skewness, kurtosis and uniformity. The main aim of the method is to increase the effectiveness and efficiency of the classification process in an objective manner to reduce the numbers of false-positive of malignancies. Three layers artificial neural network (ANN) with seven features was proposed for classifying the marked regions into benign and malignant and 90.91% sensitivity and 83.87% specificity is achieved that is very much promising compare to the radiologist's sensitivity 75%.

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          Most cited references7

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          Approaches for automated detection and classification of masses in mammograms

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            A review of evidence of health benefit from artificial neural networks in medical intervention

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              Computer-aided characterization of mammographic masses: accuracy of mass segmentation and its effects on characterization.

              Mass segmentation is used as the first step in many computer-aided diagnosis (CAD) systems for classification of breast masses as malignant or benign. The goal of this paper was to study the accuracy of an automated mass segmentation method developed in our laboratory, and to investigate the effect of the segmentation stage on the overall classification accuracy. The automated segmentation method was quantitatively compared with manual segmentation by two expert radiologists (R1 and R2) using three similarity or distance measures on a data set of 100 masses. The area overlap measures between R1 and R2, the computer and R1, and the computer and R2 were 0.76 +/- 0.13, 0.74 +/- 0.11, and 0.74 +/- 0.13, respectively. The interobserver difference in these measures between the two radiologists was compared with the corresponding differences between the computer and the radiologists. Using three similarity measures and data from two radiologists, a total of six statistical tests were performed. The difference between the computer and the radiologist segmentation was significantly larger than the interobserver variability in only one test. Two sets of texture, morphological, and spiculation features, one based on the computer segmentation, and the other based on radiologist segmentation, were extracted from a data set of 249 films from 102 patients. A classifier based on stepwise feature selection and linear discriminant analysis was trained and tested using the two feature sets. The leave-one-case-out method was used for data sampling. For case-based classification, the area Az under the receiver operating characteristic (ROC) curve was 0.89 and 0.88 for the feature sets based on the radiologist segmentation and computer segmentation, respectively. The difference between the two ROC curves was not statistically significant.
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                Author and article information

                Journal
                29 July 2010
                Article
                10.5121/ijaia.2010.1301
                1007.5129
                44272ac9-96bb-4e07-9caf-f2cfb6dae384

                http://creativecommons.org/licenses/by-nc-sa/3.0/

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                Custom metadata
                International Journal of Artificial Intelligence & Applications 1.3 (2010) 1-13
                13 pages, 10 figures
                cs.CV

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