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(L)-2-oxothiazolidine-4-carboxylate in the treatment of primary hyperoxaluria type 1.
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Abstract
To evaluate the short-term efficacy of (l)-2-oxothiaolidine-4-carboxylate (OTZ, which reduces urinary oxalate excretion in normal subjects) in the treatment of primary hyperoxaluria type 1 (PH1) in a phase II study.