The average patency time after creating an endogenous arteriovenous Brescia-Cimino fistula for hemodialysis is limited. May 1990 through October 1992, 29 PTAs were performed in 23 patients with malfunctioning hemodialysis Brescia-Cimino fistulas of the forearm, by cannulation of the venous anastomotic branch and by balloon catheter dilatation. Thirty-six venous stenoses, 7 arterial anastomotic stenoses and 1 venous occlusion were treated. In 5 patients a second dilatation became necessary due to recurrent fistula malfunction after a mean period of 5 months. Twenty-eight of 29 PTAs (96%) were immediately successful. The primary patency rates were 79% at 6 months, 61% at 1 year and 61% again at 2 years. The secondary patency rates were 90%, 83% and 83%, respectively. Three post-PTA fistula thromboses (10%) were observed: two of them were successfully treated by local fibrinolysis while in the extant case a new A-V shunt was created. In our opinion, PTA is the treatment of choice for malfunctioning Brescia-Cimino fistulas; the incidence of complications was low in our series.